1de2

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[[Image:1de2.jpg|left|200px]]
 
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==NMR STRUCTURES OF REDUCED BACTERIOPHAGE T4 GLUTAREDOXIN==
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The line below this paragraph, containing "STRUCTURE_1de2", creates the "Structure Box" on the page.
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<StructureSection load='1de2' size='340' side='right'caption='[[1de2]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1de2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DE2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DE2 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1de2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1de2 OCA], [https://pdbe.org/1de2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1de2 RCSB], [https://www.ebi.ac.uk/pdbsum/1de2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1de2 ProSAT]</span></td></tr>
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{{STRUCTURE_1de2| PDB=1de2 | SCENE= }}
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</table>
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== Function ==
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'''NMR STRUCTURES OF REDUCED BACTERIOPHAGE T4 GLUTAREDOXIN'''
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[https://www.uniprot.org/uniprot/GLRX_BPT4 GLRX_BPT4] Serves as a reducing agent for the phage-induced ribonucleotide reductase, but not for the bacterial ones. This specificity may be the result of sequence differences around the redox-active disulfide bond. The oxidized form accepts electrons from bacterial glutathione and will, in turn, reduce other small disulfides. Can also be reduced by NADPH and by bacterial thioredoxin reductase.<ref>PMID:8440680</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
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Check<jmol>
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1DE2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DE2 OCA].
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/de/1de2_consurf.spt"</scriptWhenChecked>
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==Reference==
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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Solution structures of reduced and oxidized bacteriophage T4 glutaredoxin., Wang Y, Amegbey G, Wishart DS, J Biomol NMR. 2004 May;29(1):85-90. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15017142 15017142]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Enterobacteria phage t4]]
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</jmolCheckbox>
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[[Category: Single protein]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1de2 ConSurf].
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[[Category: Wang, Y.]]
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<div style="clear:both"></div>
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[[Category: Wishart, D S.]]
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== References ==
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[[Category: Glutaredoxin]]
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<references/>
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 13:44:53 2008''
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__TOC__
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</StructureSection>
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[[Category: Escherichia virus T4]]
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[[Category: Large Structures]]
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[[Category: Wang Y]]
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[[Category: Wishart DS]]

Current revision

NMR STRUCTURES OF REDUCED BACTERIOPHAGE T4 GLUTAREDOXIN

PDB ID 1de2

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