7a8p
From Proteopedia
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==Structure of human mitochondrial RNA polymerase in complex with IMT inhibitor.== | ==Structure of human mitochondrial RNA polymerase in complex with IMT inhibitor.== | ||
| - | <StructureSection load='7a8p' size='340' side='right'caption='[[7a8p]]' scene=''> | + | <StructureSection load='7a8p' size='340' side='right'caption='[[7a8p]], [[Resolution|resolution]] 3.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7A8P OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[7a8p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7A8P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7A8P FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.5Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=R4Q:(3~{R})-1-[(2~{R})-2-[4-(2-chloranyl-4-fluoranyl-phenyl)-2-oxidanylidene-chromen-7-yl]oxypropanoyl]piperidine-3-carboxylic+acid'>R4Q</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7a8p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7a8p OCA], [https://pdbe.org/7a8p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7a8p RCSB], [https://www.ebi.ac.uk/pdbsum/7a8p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7a8p ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RPOM_HUMAN RPOM_HUMAN] DNA-dependent RNA polymerase catalyzes the transcription of mitochondrial DNA into RNA using the four ribonucleoside triphosphates as substrates.<ref>PMID:21278163</ref> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[RNA polymerase 3D structures|RNA polymerase 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Atanassov I]] | [[Category: Atanassov I]] | ||
Current revision
Structure of human mitochondrial RNA polymerase in complex with IMT inhibitor.
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Categories: Homo sapiens | Large Structures | Atanassov I | Bergbrede T | Bonekamp N | Boros J | Choidas A | Cramer P | Denzel M | Falkenberg M | Felser A | Giavalisco P | Gustafsson CM | Habenberger P | Hillen HS | Horn M | Klebl B | Koch U | Larsson NG | Li X | Menninger S | Nussbaumer P | Peter B | Unger A | Di Lucrezia R
