7ds4
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of actin capping protein in complex with twinflin-1 C-terminus tail F323K mutant== | |
| + | <StructureSection load='7ds4' size='340' side='right'caption='[[7ds4]], [[Resolution|resolution]] 1.85Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[7ds4]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DS4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DS4 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ds4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ds4 OCA], [https://pdbe.org/7ds4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ds4 RCSB], [https://www.ebi.ac.uk/pdbsum/7ds4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ds4 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CAZA1_CHICK CAZA1_CHICK] F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. CapZ may mediate the attachment of the barbed ends of actin filaments to the Z-line. | ||
| - | + | ==See Also== | |
| - | + | *[[F-actin capping protein|F-actin capping protein]] | |
| - | + | *[[Twinfilin|Twinfilin]] | |
| - | [[Category: | + | __TOC__ |
| - | [[Category: Takeda | + | </StructureSection> |
| + | [[Category: Gallus gallus]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Takeda S]] | ||
Current revision
Crystal structure of actin capping protein in complex with twinflin-1 C-terminus tail F323K mutant
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