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Urokinase 3D Structures
From Proteopedia
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{{#tree:id=OrganizedByTopic|openlevels=0| | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
| - | *Urokinase | + | *Urokinase; Domains - N terminal 21-163; Kringle 69-153; catalytic 179-431 |
**[[2i9a]] - hUK Hc N terminal - human<br /> | **[[2i9a]] - hUK Hc N terminal - human<br /> | ||
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**[[1kdu]] – hUK kringle domain - NMR<br /> | **[[1kdu]] – hUK kringle domain - NMR<br /> | ||
**[[4dva]] – hUK catalytic domain <br /> | **[[4dva]] – hUK catalytic domain <br /> | ||
| - | **[[4xsk]], [[5za7]] - hUK catalytic domain (mutant) <br /> | + | **[[4xsk]], [[5za7]], [[2o8t]] - hUK catalytic domain (mutant) <br /> |
**[[5lhs]] - UK catalytic domain (mutant) - mouse<br /> | **[[5lhs]] - UK catalytic domain (mutant) - mouse<br /> | ||
*Urokinase catalytic domain complex with inhibitors | *Urokinase catalytic domain complex with inhibitors | ||
| - | **[[ | + | ****[[1c5l]], [[1c5m]], [[1c5n]], [[1c5o]], [[1c5p]], [[1c5q]], [[1c5r]], [[1c5s]], [[1c5t]], [[1c5u]], [[1c5v]], [[1c5w]], [[1c5x]], [[1c5y]], [[1c5z]], [[3ig6]], [[4fu7]], [[4fu8]], [[4fu9]], [[4fub]] - hUK + inhibitor<br /> |
| - | + | **[[1f92]], [[1gj7]], [[1gj8]], [[1gj9]], [[1gja]], [[1gjd]], [[1o5a]], [[1o5b]], [[1sc8]], [[1vj9]], [[1vja]], [[3kgp]], [[3khv]], [[3kid]], [[3mhw]], [[3mwi]], [[4h42]], [[5wxs]], [[5wxt]] - hUK (mutant) + inhibitor<br /> | |
| - | **[[ | + | **[[6ag7]] - hUK + pyrazine inhibitor<br /> |
| - | + | **[[5za8]], [[5za9]], [[5zae]], [[5zaf]], [[5zag]], [[5zah]], [[5zaj]], [[5zc5]], [[6ag2]], [[6ag3]], [[6ag9]], [[6jyp]], [[6jyq]], [[6l04]], [[6l05]] - hUK (mutant) + pyrazine inhibitor<br /> | |
| - | **[[5yc6]], | + | **[[1fv9]], [[1gi7]], [[1gi8]], [[1gi9]], [[1gjb]], [[1gjc]], [[1o3p]], [[1o5c]] – hUK (mutant) + benzimidazole derivative <br /> |
| - | **[[1f5k]] - hUK (mutant) + benzamidine derivative<br /> | + | **[[5yc6]], [[5yc7]], [[5z1c]] - hUK (mutant) + benzylamine derivative<br /> |
| + | **[[1f5k]], [[2o8u]], [[6ag2]], [[6ag3]] - hUK (mutant) + benzamidine derivative<br /> | ||
**[[1f5l]] - hUK (mutant) + amiloride derivative<br /> | **[[1f5l]] - hUK (mutant) + amiloride derivative<br /> | ||
| - | **[[1owd]], [[1owe]], [[1owh]], [[1owi]], [[1owj]], [[1owk]], [[1sqa]], [[1sqo]], [[1u6q]], [[1sqt]], [[4fuc]], [[4fud]], [[4fue]], [[4fuf]], [[4fug]], [[4fuh]], [[4fui]], [[4fuj]]- hUK + naphthamidine inhibitor<br /> | + | **[[1owd]], [[1owe]], [[1owh]], [[1owi]], [[1owj]], [[1owk]], [[1sqa]], [[1sqo]], [[1u6q]], [[1sqt]], [[4fuc]], [[4fud]], [[4fue]], [[4fuf]], [[4fug]], [[4fuh]], [[4fui]], [[4fuj]], [[7vm6]] - hUK + naphthamidine inhibitor<br /> |
**[[6nmb]]- hUK + tranexamic acid inhibitor<br /> | **[[6nmb]]- hUK + tranexamic acid inhibitor<br /> | ||
**[[1ejn]] - hUK (mutant) + urea derivative inhibitor<br /> | **[[1ejn]] - hUK (mutant) + urea derivative inhibitor<br /> | ||
**[[2vin]], [[2vio]], [[2vip]], [[2viq]], [[2viv]], [[2viw]] - hUK (mutant) + mexiletine derivative<br /> | **[[2vin]], [[2vio]], [[2vip]], [[2viq]], [[2viv]], [[2viw]] - hUK (mutant) + mexiletine derivative<br /> | ||
| - | **[[6xvd]] - hUK + peptide inhibitor<br /> | + | **[[6xvd]], [[1lmw]] - hUK + peptide inhibitor<br /> |
| - | **[[3qn7]], [[4jk5]], [[4jk6]], [[4x1n]], [[4x1q]], [[4x1r]], [[4x1s]], [[4x0w]], [[4x1p]], [[4zhl]], [[4zhm]], [[4zkn]], [[4zko]], [[4zkr]], [[4zks]], [[5wxo]], [[5wxp]], [[5wxq]], [[5wxr]], [[5wxf]] - hUK (mutant) + peptide inhibitor<br /> | + | **[[3ox7]], [[3oy5]], [[3oy6]], [[3qn7]], [[4jk5]], [[4jk6]], [[4x1n]], [[4x1q]], [[4x1r]], [[4x1s]], [[4x0w]], [[4x1p]], [[4zhl]], [[4zhm]], [[4zkn]], [[4zko]], [[4zkr]], [[4zks]], [[5wxo]], [[5wxp]], [[5wxq]], [[5wxr]], [[5wxf]] - hUK (mutant) + peptide inhibitor<br /> |
| - | **[[2nwn]], [[3m61]], [[4gly]], [[4mnw]], [[4mnx]], [[4mny]], [[4os1]], [[4os2]], [[4os4]], [[4os5]], [[4os6]], [[4os7]] - hUK (mutant) + bicyclic peptide <br /> | + | **[[7zrr]], [[7zrt]] - hUK + bicyclic peptide <br /> |
| - | **[[2vnt]], [[2r2w]] - hUK + guanidine derivative<br /> | + | **[[2nwn]], [[3m61]], [[4gly]], [[4mnw]], [[4mnv]], [[4mnx]], [[4mny]], [[4os1]], [[4os2]], [[4os4]], [[4os5]], [[4os6]], [[4os7]] - hUK (mutant) + bicyclic peptide <br /> |
| + | **[[6xvd]] - hUK catalytic domain + upain-1 peptide<br /> | ||
| + | **[[2o8w]], [[2vnt]], [[2r2w]], [[7vm5]] - hUK + guanidine derivative<br /> | ||
**[[5xg4]] - hUK + quercetin<br /> | **[[5xg4]] - hUK + quercetin<br /> | ||
**[[1w0z]], [[1w10]], [[1w11]], [[1w12]], [[1w13]], [[1w14]] - hUK + alanineamide derivative<br /> | **[[1w0z]], [[1w10]], [[1w11]], [[1w12]], [[1w13]], [[1w14]] - hUK + alanineamide derivative<br /> | ||
| + | **[[7dzd]], [[7vm4]], [[7vm7]] - hUK + drug<br /> | ||
**[[6a8g]], [[6a8n]] - mUK (mutant) + cyclic peptide <br /> | **[[6a8g]], [[6a8n]] - mUK (mutant) + cyclic peptide <br /> | ||
Current revision
3D Structures of urokinase
Updated on 14-March-2024 - For a general description of the protein see Urokinase
