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7dsw
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of a human NHE1-CHP1 complex under pH 7.5== | |
| - | + | <StructureSection load='7dsw' size='340' side='right'caption='[[7dsw]], [[Resolution|resolution]] 3.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7dsw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DSW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DSW FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.3Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LBN:1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine'>LBN</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7dsw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7dsw OCA], [https://pdbe.org/7dsw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7dsw RCSB], [https://www.ebi.ac.uk/pdbsum/7dsw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7dsw ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SL9A1_HUMAN SL9A1_HUMAN] Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.<ref>PMID:8901634</ref> <ref>PMID:11350981</ref> <ref>PMID:15035633</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Dong Y]] | ||
| + | [[Category: Gao Y]] | ||
| + | [[Category: Li B]] | ||
| + | [[Category: Zhang XC]] | ||
| + | [[Category: Zhao Y]] | ||
Current revision
Structure of a human NHE1-CHP1 complex under pH 7.5
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Categories: Homo sapiens | Large Structures | Dong Y | Gao Y | Li B | Zhang XC | Zhao Y
