7duo
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of daratumumab fab and CD38 complex== | |
| + | <StructureSection load='7duo' size='340' side='right'caption='[[7duo]], [[Resolution|resolution]] 2.81Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[7duo]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DUO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DUO FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.81Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7duo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7duo OCA], [https://pdbe.org/7duo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7duo RCSB], [https://www.ebi.ac.uk/pdbsum/7duo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7duo ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CD38_HUMAN CD38_HUMAN] Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system. | ||
| - | + | ==See Also== | |
| - | + | *[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: Wang | + | [[Category: Homo sapiens]] |
| - | [[Category: Yu | + | [[Category: Large Structures]] |
| - | [[Category: Yu | + | [[Category: Wang L]] |
| + | [[Category: Yu CF]] | ||
| + | [[Category: Yu XJ]] | ||
Current revision
Crystal structure of daratumumab fab and CD38 complex
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Categories: Homo sapiens | Large Structures | Wang L | Yu CF | Yu XJ
