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7k5e

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Current revision (15:17, 18 October 2023) (edit) (undo)
 
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<StructureSection load='7k5e' size='340' side='right'caption='[[7k5e]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
<StructureSection load='7k5e' size='340' side='right'caption='[[7k5e]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[7k5e]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7K5E OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=7K5E FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7k5e]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7K5E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7K5E FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=VXM:4-{[(5-fluoro-2-hydroxyphenyl)methyl]amino}-1H-isoindole-1,3(2H)-dione'>VXM</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">bfrB, PA3531 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=VXM:4-{[(5-fluoro-2-hydroxyphenyl)methyl]amino}-1H-isoindole-1,3(2H)-dione'>VXM</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferroxidase Ferroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.3.1 1.16.3.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7k5e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7k5e OCA], [https://pdbe.org/7k5e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7k5e RCSB], [https://www.ebi.ac.uk/pdbsum/7k5e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7k5e ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7k5e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7k5e OCA], [http://pdbe.org/7k5e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7k5e RCSB], [http://www.ebi.ac.uk/pdbsum/7k5e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7k5e ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/Q9HY79_PSEAE Q9HY79_PSEAE]] Iron-storage protein (By similarity). Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex (By similarity).[PIRNR:PIRNR002560]
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[https://www.uniprot.org/uniprot/Q9HY79_PSEAE Q9HY79_PSEAE] Iron-storage protein (By similarity). Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex (By similarity).[PIRNR:PIRNR002560]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 7k5e" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 7k5e" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Ferritin 3D structures|Ferritin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ferroxidase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Pseae]]
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[[Category: Pseudomonas aeruginosa PAO1]]
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[[Category: Annor-Gyamfi, J K]]
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[[Category: Annor-Gyamfi JK]]
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[[Category: Battaile, K P]]
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[[Category: Battaile KP]]
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[[Category: Bunce, R A]]
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[[Category: Bunce RA]]
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[[Category: Lovell, S]]
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[[Category: Lovell S]]
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[[Category: Meraz, K]]
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[[Category: Meraz K]]
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[[Category: Punchi-Hewage, A]]
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[[Category: Punchi-Hewage A]]
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[[Category: Rivera, M]]
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[[Category: Rivera M]]
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[[Category: Soldano, A]]
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[[Category: Soldano A]]
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[[Category: Yao, H]]
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[[Category: Yao H]]
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[[Category: Biofilm]]
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[[Category: Electron transport]]
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[[Category: Iron binding]]
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[[Category: Iron mobilization]]
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[[Category: Iron storage]]
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[[Category: Oxidoreductase]]
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[[Category: Protein-protein interaction inhibitor]]
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Current revision

1.75 A resolution structure of WT BfrB from Pseudomonas aeruginosa in complex with a protein-protein interaction inhibitor JAG-5-7

PDB ID 7k5e

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