2alf

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:18, 15 May 2024) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='2alf' size='340' side='right'caption='[[2alf]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='2alf' size='340' side='right'caption='[[2alf]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2alf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ALF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ALF FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2alf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ALF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ALF FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CyPA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2alf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2alf OCA], [https://pdbe.org/2alf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2alf RCSB], [https://www.ebi.ac.uk/pdbsum/2alf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2alf ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2alf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2alf OCA], [https://pdbe.org/2alf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2alf RCSB], [https://www.ebi.ac.uk/pdbsum/2alf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2alf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/PPIA_HUMAN PPIA_HUMAN]] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
+
[https://www.uniprot.org/uniprot/PPIA_HUMAN PPIA_HUMAN] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 26: Line 25:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Peptidylprolyl isomerase]]
+
[[Category: Bi R-C]]
-
[[Category: Bi, R C]]
+
[[Category: Chen M-E]]
-
[[Category: Chen, M E]]
+
[[Category: Han Y]]
-
[[Category: Han, Y]]
+
[[Category: Hu H]]
-
[[Category: Hu, H]]
+
[[Category: Huang C-Q]]
-
[[Category: Huang, C Q]]
+
[[Category: Liu H-L]]
-
[[Category: Liu, H L]]
+
[[Category: Yu L]]
-
[[Category: Yu, L]]
+
-
[[Category: Isomerase]]
+

Current revision

crystal structure of human CypA mutant K131A

PDB ID 2alf

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools