2aq2

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<StructureSection load='2aq2' size='340' side='right'caption='[[2aq2]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='2aq2' size='340' side='right'caption='[[2aq2]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2aq2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885] and [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AQ2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2aq2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AQ2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2apb|2apb]], [[2apf|2apf]], [[2apt|2apt]], [[2apv|2apv]], [[2apw|2apw]], [[2apx|2apx]], [[2aq1|2aq1]], [[2aq3|2aq3]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">entC3 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 "Micrococcus aureus" (Rosenbach 1884) Zopf 1885])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2aq2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aq2 OCA], [https://pdbe.org/2aq2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2aq2 RCSB], [https://www.ebi.ac.uk/pdbsum/2aq2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2aq2 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2aq2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aq2 OCA], [https://pdbe.org/2aq2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2aq2 RCSB], [https://www.ebi.ac.uk/pdbsum/2aq2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2aq2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/ENTC3_STAAU ENTC3_STAAU]] Staphylococcal enterotoxins cause the intoxication staphylococcal food poisoning syndrome. The illness is characterized by high fever, hypotension, diarrhea, shock, and in some cases death.
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[https://www.uniprot.org/uniprot/TVB5_MOUSE TVB5_MOUSE]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/aq/2aq2_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/aq/2aq2_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lk3 transgenic mice]]
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[[Category: Mus musculus]]
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[[Category: Cho, S]]
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[[Category: Staphylococcus aureus]]
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[[Category: Guan, R]]
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[[Category: Cho S]]
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[[Category: Kerzic, M C]]
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[[Category: Guan R]]
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[[Category: Kieke, M C]]
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[[Category: Kerzic MC]]
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[[Category: Kranz, D M]]
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[[Category: Kieke MC]]
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[[Category: Mariuzza, R A]]
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[[Category: Kranz DM]]
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[[Category: Sundberg, E J]]
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[[Category: Mariuzza RA]]
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[[Category: Swaminathan, C P]]
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[[Category: Sundberg EJ]]
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[[Category: Yang, J]]
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[[Category: Swaminathan CP]]
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[[Category: Complex structure]]
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[[Category: Yang J]]
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[[Category: Immune system]]
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[[Category: Staphlococcal enterotoxin c3]]
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[[Category: T-cell receptor v beta domain]]
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Current revision

Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3 mutant

PDB ID 2aq2

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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