3D structures of ubiquitin conjugating enzyme

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(New page: == 3D Structures of ubiquitin conjugating enzyme == Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} - For a general description of the protein see [[Ubiquitin...)
Current revision (11:04, 26 February 2024) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 7: Line 7:
**[[1jas]] – hUbc – human <BR />
**[[1jas]] – hUbc – human <BR />
 +
**[[8wr5]] – hUbc (mutant)<BR />
**[[2aak]] – AtUbc – ''Arabidopsis thaliana'' <BR />
**[[2aak]] – AtUbc – ''Arabidopsis thaliana'' <BR />
**[[2qcq]], [[1fzy]] – yUbc – yeast <BR />
**[[2qcq]], [[1fzy]] – yUbc – yeast <BR />
Line 15: Line 16:
**[[2h2y]] – PfUbc – ''Plasmodium falciparum'' <BR />
**[[2h2y]] – PfUbc – ''Plasmodium falciparum'' <BR />
**[[6mj9]], [[5vor]] – Ubc – ''Naegleria fowleri'' <BR />
**[[6mj9]], [[5vor]] – Ubc – ''Naegleria fowleri'' <BR />
 +
**[[1yf9]] – Ubc – ''Leishmania major'' <BR />
 +
**[[7wlh]] – Ubc – African swine fever virus <BR />
*Ubiquitin conjugating enzyme 1
*Ubiquitin conjugating enzyme 1
Line 28: Line 31:
**[[1ayz]] – yUbc <BR />
**[[1ayz]] – yUbc <BR />
**[[4r62]] – yUbc + ubiquitin carboxyl extension protein 80 <BR />
**[[4r62]] – yUbc + ubiquitin carboxyl extension protein 80 <BR />
 +
**[[7mex]], [[7mey]] – yUbc + ubiquitin + degron + E3 – Cryo EM <BR />
**[[5aie]] – yUbc + NOT4 <BR />
**[[5aie]] – yUbc + NOT4 <BR />
**[[1z2u]] – CeUbc <BR />
**[[1z2u]] – CeUbc <BR />
Line 48: Line 52:
**[[2awf]], [[2cyx]] – hUbc<BR />
**[[2awf]], [[2cyx]] – hUbc<BR />
 +
**[[6xxu]] – hUbc - NMR <BR />
 +
**[[7v8f]] – hUbc + E3 <BR />
 +
**[[7oik]] – hUbc + E3 – Cryo EM<BR />
**[[6xxu]] – hUbc - NMR<BR />
**[[6xxu]] – hUbc - NMR<BR />
**[[1c4z]] – hUbc + E3 HECT domain <BR />
**[[1c4z]] – hUbc + E3 HECT domain <BR />
 +
**[[7v8f]] – hUbc + E3 ubiquitin protein ligase RNF31 <BR />
 +
**[[8eb0]] – hUbc + E3 ubiquitin protein ligase RNF216 + Ub <BR />
**[[1fbv]] – hUbc + E3 Cbl + ZAP-70 peptide<BR />
**[[1fbv]] – hUbc + E3 Cbl + ZAP-70 peptide<BR />
**[[4jqu]] – hUbc + U7BR <BR />
**[[4jqu]] – hUbc + U7BR <BR />
Line 60: Line 69:
**[[5tte]], [[5udh]] – hUbc (mutant) + ubiquitin + ARIH1<BR />
**[[5tte]], [[5udh]] – hUbc (mutant) + ubiquitin + ARIH1<BR />
**[[5hpt]] – hUbc + ubiquitin + NEDD4-like E3 ubiquitin-protein<BR />
**[[5hpt]] – hUbc + ubiquitin + NEDD4-like E3 ubiquitin-protein<BR />
 +
**[[7b5l]], [[7b5n]] – hUbc + hPolyUBB-C + Cul1 + Nedd8 + RBX1 + ARITH1 – Cryo EM<br />
 +
**[[8pmq]] – hUbc in Ube2R-GID/CTLH complex – Cryo EM<br />
**[[2ucz]] – yUbc <BR />
**[[2ucz]] – yUbc <BR />
Line 119: Line 130:
**[[4whv]], [[6s53]] – hUbc + ubiquitin + E3 ubiquitin-protein ligase<BR />
**[[4whv]], [[6s53]] – hUbc + ubiquitin + E3 ubiquitin-protein ligase<BR />
**[[5ait]], [[5aiu]] – hUbc + ubiquitin + E3 ubiquitin-protein ligase RNF4<BR />
**[[5ait]], [[5aiu]] – hUbc + ubiquitin + E3 ubiquitin-protein ligase RNF4<BR />
 +
**[[7bbf]], [[7myh]] – hUbc + polyubiquitin-C <BR />
 +
**[[6ulh]], [[6ump]], [[6ums]], [[7bxg]] – hUbc + polyubiquitin-C + MavC<BR />
 +
**[[7bbd]] – hUbc + polyubiquitin-C + E3<BR />
**[[4orh]] – hUbc/Mms2 + E3 ubiquitin-protein ligase RN8<BR />
**[[4orh]] – hUbc/Mms2 + E3 ubiquitin-protein ligase RN8<BR />
**[[4ip3]], [[3w31]] – hUbc + Orf169b <BR />
**[[4ip3]], [[3w31]] – hUbc + Orf169b <BR />
**[[2oxq]] – Ubc + CHIP U-box - zebrafish<BR />
**[[2oxq]] – Ubc + CHIP U-box - zebrafish<BR />
 +
**[[6zhs]], [[6zht]] – yUbc + E1<BR />
**[[5ojw]] – yUbc + Mms2 <BR />
**[[5ojw]] – yUbc + Mms2 <BR />
**[[6jky]] – yUbc + ubiquitin + MvcA <BR />
**[[6jky]] – yUbc + ubiquitin + MvcA <BR />
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**[[2mt6]] – hUbc - NMR <BR />
**[[2mt6]] – hUbc - NMR <BR />
 +
**[[8a58]] – hUbc + E3 ubiquitin-protein ligase TRIM21<BR />
 +
 +
*Ubiquitin conjugating enzyme 20
 +
 +
**[[7yw1l]] – Ubc – Trametes pubescens<br />
*Ubiquitin conjugating enzyme A or Rad6
*Ubiquitin conjugating enzyme A or Rad6
Line 134: Line 154:
**[[6cyo]] – hUbc A<br />
**[[6cyo]] – hUbc A<br />
**[[6cyr]] – hUbc A (mutant)<br />
**[[6cyr]] – hUbc A (mutant)<br />
 +
**[[8btl]] – hUbc + Ubr4<br />
 +
**[[8iej]] – hUbc A in nucleosome complex – Cryo EM <BR />
*Ubiquitin conjugating enzyme B
*Ubiquitin conjugating enzyme B
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**[[4ap4]] – hUbc D1 + E3 ubiquitin-protein ligase RNF4 + ubiquitin<BR />
**[[4ap4]] – hUbc D1 + E3 ubiquitin-protein ligase RNF4 + ubiquitin<BR />
**[[3oj4]] – hUbc D1 + tumor necrosis factor α-induced protein 3 + ubiquitin<BR />
**[[3oj4]] – hUbc D1 + tumor necrosis factor α-induced protein 3 + ubiquitin<BR />
 +
**[[7zj3]] – hUbc D1 (mutant) + TRIM2 + p;olyubiquitin-C<BR />
*Ubiquitin conjugating enzyme D2
*Ubiquitin conjugating enzyme D2
**[[2esk]], [[2clw]], [[3l1y]], [[3tgd]] – hUbc D2 <BR />
**[[2esk]], [[2clw]], [[3l1y]], [[3tgd]] – hUbc D2 <BR />
-
**[[2eso]], [[2esp]], [[2esq]] – hUbc D2 (mutant)<BR />
+
**[[2eso]], [[2esp]], [[2esq]] – hUbc, [[7bol]]D2 (mutant)<BR />
**[[1w4u]] – hUbc D2 - NMR<BR />
**[[1w4u]] – hUbc D2 - NMR<BR />
**[[4ddg]], [[4ddi]], [[5ulf]] – hUbc D2 + ubiquitin<BR />
**[[4ddg]], [[4ddi]], [[5ulf]] – hUbc D2 + ubiquitin<BR />
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**[[4ldt]] – hUbc D2 + Otub1 + ubiquitin <BR />
**[[4ldt]] – hUbc D2 + Otub1 + ubiquitin <BR />
**[[5d1k]], [[5d1l]], [[5d1m]] – hUbc D2 + E3 ubiquitin-protein ligase RNF25<BR />
**[[5d1k]], [[5d1l]], [[5d1m]] – hUbc D2 + E3 ubiquitin-protein ligase RNF25<BR />
 +
**[[8gbq]] – hUbc D2 + E3 ubiquitin-protein ligase RNF125<BR />
**[[5edv]] – hUbc D2 + ubiquitin + E3 ubiquitin-protein ligase RNF31<BR />
**[[5edv]] – hUbc D2 + ubiquitin + E3 ubiquitin-protein ligase RNF31<BR />
**[[4a49]] – hUbc D2 + E3 ubiquitin-protein ligase CBL-B<BR />
**[[4a49]] – hUbc D2 + E3 ubiquitin-protein ligase CBL-B<BR />
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**[[5d0k]], [[5d0m]] – hUbc D2 + UBB + RING finger protein 165<BR />
**[[5d0k]], [[5d0m]] – hUbc D2 + UBB + RING finger protein 165<BR />
**[[4ldt]] – hUbc D2 (mutant) + ubiquitin + otub1 + ubiquitin aldehyde<BR />
**[[4ldt]] – hUbc D2 (mutant) + ubiquitin + otub1 + ubiquitin aldehyde<BR />
-
**[[4wz3]] – hUbc D2 + E3 ubiquitin-protein ligase LubX<BR />
+
**[[4wz3]], [[6w7z]] – hUbc D2 + E3 ubiquitin-protein ligase LubX<BR />
 +
**[[7ahz]], [[7ai0]], [[7ai1]], [[7r71]] – hUbc D2 + E3 ubiquitin-protein ligase RNF165+ Ub<BR />
 +
**[[6w7z]], [[6w9d]] – hUbc D2 + E3 ubiquitin-protein ligase RLIM + Ub<BR />
 +
**[[8b3i]] – hUbc D2 + E3 ubiquitin-protein ligase RBX1 + polyubiqiutin-C + NEDD8 – Cryo EM<BR />
**[[5v2w]] – hUbc D2 (mutant) + ubiquitin + TRIM23<BR />
**[[5v2w]] – hUbc D2 (mutant) + ubiquitin + TRIM23<BR />
**[[1ur6]] – hUbc D2 + Cnot4 - NMR<BR />
**[[1ur6]] – hUbc D2 + Cnot4 - NMR<BR />
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**[[6cp0]] – hUbc D3 + SdcA<BR />
**[[6cp0]] – hUbc D3 + SdcA<BR />
**[[6t7f]] – hUbc D3 + ubiquitin + E3 ubiquitin-protein ligase MYCBP2<BR />
**[[6t7f]] – hUbc D3 + ubiquitin + E3 ubiquitin-protein ligase MYCBP2<BR />
 +
**[[7lyb]], [[8grq]], [[8smw]], [[8smy]], [[8u14]], [[8upf]] – hUbc D3 in nucleosome complex – Cryo EM <BR />
 +
**[[7jzv]], [[8smw]], [[8smx]], [[8smz]], [[8sn0]], [[8sn1]], [[8sn2]], [[8sn3]], [[8sn4]], [[8sn5]], [[8sn7]], [[8sn8]] – hUbc D3 (mutant) in nucleosome complex – Cryo EM <BR />
*Ubiquitin conjugating enzyme E1
*Ubiquitin conjugating enzyme E1
-
**[[3bzh]] – hUbc E1 <BR />
+
**[[3bzh]], [[5lbn]] – hUbc E1 <BR />
 +
**[[8iya]] – hUbc E1 (mutant) + SETDB1 peptide<BR />
**[[6fga]] – hUbc E1 + E3 TRIM21 <BR />
**[[6fga]] – hUbc E1 + E3 TRIM21 <BR />
*Ubiquitin conjugating enzyme E2
*Ubiquitin conjugating enzyme E2
-
**[[6w9a]] – hUbc E2 + E3 RLIM <BR />
+
**[[6w9a]] – hUbc E2 + E3 ubiquitin-protein ligase RLIM <BR />
*Ubiquitin conjugating enzyme G1
*Ubiquitin conjugating enzyme G1
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**[[2lxp]] – hUbc + AMFR peptide - NMR<BR />
**[[2lxp]] – hUbc + AMFR peptide - NMR<BR />
**[[3h8k]], [[4lad]] – hUbc + AMFR peptide <BR />
**[[3h8k]], [[4lad]] – hUbc + AMFR peptide <BR />
 +
**[[7lew]] – hUbc + AUP1 peptide <BR />
*Ubiquitin conjugating enzyme H
*Ubiquitin conjugating enzyme H
Line 220: Line 251:
*Ubiquitin conjugating enzyme K
*Ubiquitin conjugating enzyme K
-
**[[5dfl]], [[6if1]] – hUbc + ubiquitin <BR />
+
**[[5dfl]], [[6if1]], [[7myf]] – hUbc + ubiquitin <BR />
-
[[6jb6]], [[6jb7]] – hUbc (mutant) + ubiquitin <BR />
+
**[[6jb6]], [[6jb7]] – hUbc (mutant) + ubiquitin <BR />
 +
**[[7ojx]] – hUbc + polyubiquitin-B + E3 ubiquitin-protein ligase RNF38<BR />
 +
*Ubiquitin conjugating enzyme L6
 +
 +
**[[8se9]], [[8sea]], [[8sv8]] – hUbc + Uba7 + ISG15 – Cryo EM <BR />
*Ubiquitin conjugating enzyme Q1
*Ubiquitin conjugating enzyme Q1
Line 229: Line 264:
*Ubiquitin conjugating enzyme R1
*Ubiquitin conjugating enzyme R1
-
**[[3rz3]] – hUbc + inhibitor <BR />
+
**[[3rz3]], [[7m2k]] – hUbc + inhibitor <BR />
**[[4mdk]] – hUbc + ubiquitin + inhibitor <BR />
**[[4mdk]] – hUbc + ubiquitin + inhibitor <BR />
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**[[6nyo]] – hUbc R2 + ubiquitin <BR />
**[[6nyo]] – hUbc R2 + ubiquitin <BR />
 +
**[[8pql]], [[8q7r]] – hUbcR2 in cullin-ring ligase complex – Cryo EM<BR />
*Ubiquitin conjugating enzyme S
*Ubiquitin conjugating enzyme S
**[[1zdn]] – hUbc <BR />
**[[1zdn]] – hUbc <BR />
 +
**[[7ahf]] – hUbc (mutant)<BR />
**[[6qhk]], [[6s98]] – hUbc catalytic domain<BR />
**[[6qhk]], [[6s98]] – hUbc catalytic domain<BR />
**[[6qh3]], [[6s96]] – hUbc catalytic domain (mutant)<BR />
**[[6qh3]], [[6s96]] – hUbc catalytic domain (mutant)<BR />
Line 247: Line 284:
**[[6r75]] – hUbc T (mutant) <BR />
**[[6r75]] – hUbc T (mutant) <BR />
**[[4ccg]] – hUbc T + E3 ubiquitin-protein ligase Fancl<BR />
**[[4ccg]] – hUbc T + E3 ubiquitin-protein ligase Fancl<BR />
 +
**[[8jve]] – hUbc + inhibitor<BR />
*Ubiquitin conjugating enzyme Uev-1
*Ubiquitin conjugating enzyme Uev-1
Line 261: Line 299:
**[[6op8]] – fyUbc + CUE domain-containing protein 4 <BR />
**[[6op8]] – fyUbc + CUE domain-containing protein 4 <BR />
 +
 +
*Ubiquitin conjugating enzyme E2-21KDa
 +
 +
**[[2y9m]] – yUbc Ubc domain 15-183 + peroxisome assembly protein <BR />
*Ubiquitin conjugating enzyme E2-25KDa (Huntington interacting protein 2 HIP-2)
*Ubiquitin conjugating enzyme E2-25KDa (Huntington interacting protein 2 HIP-2)
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**[[3f92]] – hHIP-2/azorectase (mutant) <BR />
**[[3f92]] – hHIP-2/azorectase (mutant) <BR />
**[[3k9o]], [[3k9p]] – hHIP-2 + ubiquitin <BR />
**[[3k9o]], [[3k9p]] – hHIP-2 + ubiquitin <BR />
 +
 +
**Ubiquitin conjugating enzyme E2-34KDa
 +
 +
**[[6zhu]], [[7k5j]] – yUbc + E1 + ATP <BR />
 +
 +
*Ubiquitin conjugating enzyme E2-230KDa
 +
 +
**[[7un6]] – yUbc + NAP1L1 – Cryo EM <BR />
}}
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

3D Structures of ubiquitin conjugating enzyme

Updated on 26-February-2024 - For a general description of the protein see Ubiquitin conjugating enzyme

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

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