7ljd

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(New page: '''Unreleased structure''' The entry 7ljd is ON HOLD Authors: Zhuang, Y., Krumm, B., Zhang, H., Zhou, X.E., Wang, Y., Guo, J., Huang, X.-P., Liu, Y., Wang, L., Cheng, X., Jiang, Y., Jia...)
Current revision (11:33, 30 October 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 7ljd is ON HOLD
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==Allosteric modulator LY3154207 binding to dopamine-bound dopamine receptor 1 in complex with miniGs protein==
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<StructureSection load='7ljd' size='340' side='right'caption='[[7ljd]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7ljd]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Lama_glama Lama glama] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7LJD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7LJD FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=G4C:2-[2,6-bis(chloranyl)phenyl]-1-[(1~{S},3~{R})-3-(hydroxymethyl)-1-methyl-5-(3-methyl-3-oxidanyl-butyl)-3,4-dihydro-1~{H}-isoquinolin-2-yl]ethanone'>G4C</scene>, <scene name='pdbligand=LDP:L-DOPAMINE'>LDP</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ljd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ljd OCA], [https://pdbe.org/7ljd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ljd RCSB], [https://www.ebi.ac.uk/pdbsum/7ljd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ljd ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DRD1_HUMAN DRD1_HUMAN] Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
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Authors: Zhuang, Y., Krumm, B., Zhang, H., Zhou, X.E., Wang, Y., Guo, J., Huang, X.-P., Liu, Y., Wang, L., Cheng, X., Jiang, Y., Jiang, H., Melcher, K., Zhang, C., Yi, W., Roth, B.L., Zhang, Y., Xu, H.E.
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==See Also==
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*[[Dopamine receptor 3D structures|Dopamine receptor 3D structures]]
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Description: Allosteric modulator LY3154207 binding to dopamine-bound dopamine receptor 1 in complex with miniGs protein
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*[[Transducin 3D structures|Transducin 3D structures]]
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[[Category: Unreleased Structures]]
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__TOC__
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[[Category: Zhou, X.E]]
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</StructureSection>
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[[Category: Xu, H.E]]
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[[Category: Bos taurus]]
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[[Category: Zhang, H]]
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[[Category: Homo sapiens]]
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[[Category: Huang, X.-P]]
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[[Category: Lama glama]]
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[[Category: Guo, J]]
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[[Category: Large Structures]]
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[[Category: Melcher, K]]
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[[Category: Rattus norvegicus]]
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[[Category: Krumm, B]]
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[[Category: Cheng X]]
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[[Category: Yi, W]]
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[[Category: Guo J]]
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[[Category: Jiang, Y]]
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[[Category: Huang X-P]]
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[[Category: Wang, Y]]
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[[Category: Jiang H]]
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[[Category: Zhang, Y]]
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[[Category: Jiang Y]]
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[[Category: Zhuang, Y]]
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[[Category: Krumm B]]
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[[Category: Roth, B.L]]
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[[Category: Liu Y]]
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[[Category: Wang, L]]
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[[Category: Melcher K]]
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[[Category: Jiang, H]]
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[[Category: Roth BL]]
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[[Category: Cheng, X]]
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[[Category: Wang L]]
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[[Category: Liu, Y]]
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[[Category: Wang Y]]
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[[Category: Zhang, C]]
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[[Category: Xu HE]]
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[[Category: Yi W]]
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[[Category: Zhang C]]
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[[Category: Zhang H]]
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[[Category: Zhang Y]]
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[[Category: Zhou XE]]
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[[Category: Zhuang Y]]

Current revision

Allosteric modulator LY3154207 binding to dopamine-bound dopamine receptor 1 in complex with miniGs protein

PDB ID 7ljd

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OCA

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