2ddi
From Proteopedia
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==NMR structure of the second Kunitz domain of human WFIKKN1== | ==NMR structure of the second Kunitz domain of human WFIKKN1== | ||
| - | <StructureSection load='2ddi' size='340' side='right'caption='[[2ddi | + | <StructureSection load='2ddi' size='340' side='right'caption='[[2ddi]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2ddi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2ddi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DDI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DDI FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr> |
| - | + | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ddi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ddi OCA], [https://pdbe.org/2ddi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ddi RCSB], [https://www.ebi.ac.uk/pdbsum/2ddi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ddi ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ddi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ddi OCA], [https://pdbe.org/2ddi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ddi RCSB], [https://www.ebi.ac.uk/pdbsum/2ddi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ddi ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/WFKN1_HUMAN WFKN1_HUMAN] Protease-inhibitor that contains multiple distinct protease inhibitor domains. Probably has serine protease- and metalloprotease-inhibitor activity (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dd/2ddi_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dd/2ddi_consurf.spt"</scriptWhenChecked> | ||
| - | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> |
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Liepinsh | + | [[Category: Liepinsh E]] |
| - | [[Category: Otting | + | [[Category: Otting G]] |
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Current revision
NMR structure of the second Kunitz domain of human WFIKKN1
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