This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2dk3

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (18:42, 29 May 2024) (edit) (undo)
 
Line 1: Line 1:
==Solution structure of Mib-herc2 domain in HECT domain containing protein 1==
==Solution structure of Mib-herc2 domain in HECT domain containing protein 1==
-
<StructureSection load='2dk3' size='340' side='right'caption='[[2dk3]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
+
<StructureSection load='2dk3' size='340' side='right'caption='[[2dk3]]' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2dk3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DK3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DK3 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2dk3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DK3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DK3 FirstGlance]. <br>
-
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HECTD1, KIAA1131 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dk3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dk3 OCA], [https://pdbe.org/2dk3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dk3 RCSB], [https://www.ebi.ac.uk/pdbsum/2dk3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dk3 ProSAT], [https://www.topsan.org/Proteins/RSGI/2dk3 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dk3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dk3 OCA], [https://pdbe.org/2dk3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dk3 RCSB], [https://www.ebi.ac.uk/pdbsum/2dk3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dk3 ProSAT], [https://www.topsan.org/Proteins/RSGI/2dk3 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/HECD1_HUMAN HECD1_HUMAN]] Probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. May be required for development of the head mesenchyme and neural tube closure (By similarity).
+
[https://www.uniprot.org/uniprot/HECD1_HUMAN HECD1_HUMAN] Probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. May be required for development of the head mesenchyme and neural tube closure (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 24: Line 24:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: He, F]]
+
[[Category: He F]]
-
[[Category: Inoue, M]]
+
[[Category: Inoue M]]
-
[[Category: Kigawa, T]]
+
[[Category: Kigawa T]]
-
[[Category: Muto, Y]]
+
[[Category: Muto Y]]
-
[[Category: Structural genomic]]
+
[[Category: Shirouzu M]]
-
[[Category: Shirouzu, M]]
+
[[Category: Terada T]]
-
[[Category: Terada, T]]
+
[[Category: Yokoyama S]]
-
[[Category: Yokoyama, S]]
+
-
[[Category: Hect domain containing protein 1]]
+
-
[[Category: Mib-herc2 domain]]
+
-
[[Category: National project on protein structural and functional analyse]]
+
-
[[Category: Nppsfa]]
+
-
[[Category: Protein binding]]
+
-
[[Category: Rsgi]]
+

Current revision

Solution structure of Mib-herc2 domain in HECT domain containing protein 1

PDB ID 2dk3

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools