2dm8

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Current revision (18:43, 29 May 2024) (edit) (undo)
 
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==Solution structure of the eighth PDZ domain of human InaD-like protein==
==Solution structure of the eighth PDZ domain of human InaD-like protein==
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<StructureSection load='2dm8' size='340' side='right'caption='[[2dm8]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2dm8' size='340' side='right'caption='[[2dm8]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2dm8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DM8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DM8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2dm8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DM8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DM8 FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">INADL, PATJ ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dm8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dm8 OCA], [https://pdbe.org/2dm8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dm8 RCSB], [https://www.ebi.ac.uk/pdbsum/2dm8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dm8 ProSAT], [https://www.topsan.org/Proteins/RSGI/2dm8 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dm8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dm8 OCA], [https://pdbe.org/2dm8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dm8 RCSB], [https://www.ebi.ac.uk/pdbsum/2dm8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dm8 ProSAT], [https://www.topsan.org/Proteins/RSGI/2dm8 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/INADL_HUMAN INADL_HUMAN]] Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons.<ref>PMID:11927608</ref>
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[https://www.uniprot.org/uniprot/INADL_HUMAN INADL_HUMAN] Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons.<ref>PMID:11927608</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Hayashi, F]]
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[[Category: Hayashi F]]
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[[Category: Inoue, K]]
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[[Category: Inoue K]]
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[[Category: Nagashima, T]]
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[[Category: Nagashima T]]
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[[Category: Structural genomic]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S]]
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[[Category: Hinadl]]
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[[Category: Inad-like protein]]
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[[Category: Inadl]]
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[[Category: Inadl protein]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Pals1-associated tight junction protein]]
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[[Category: Patj]]
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[[Category: Pdz domain]]
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[[Category: Protein associated to tight junction]]
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[[Category: Protein binding]]
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[[Category: Rsgi]]
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Current revision

Solution structure of the eighth PDZ domain of human InaD-like protein

PDB ID 2dm8

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