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2dmt

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Current revision (18:44, 29 May 2024) (edit) (undo)
 
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==Solution structure of the homeobox domain of Homeobox protein BarH-like 1==
==Solution structure of the homeobox domain of Homeobox protein BarH-like 1==
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<StructureSection load='2dmt' size='340' side='right'caption='[[2dmt]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2dmt' size='340' side='right'caption='[[2dmt]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2dmt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DMT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DMT FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2dmt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DMT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DMT FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BARX1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dmt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dmt OCA], [https://pdbe.org/2dmt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dmt RCSB], [https://www.ebi.ac.uk/pdbsum/2dmt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dmt ProSAT], [https://www.topsan.org/Proteins/RSGI/2dmt TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dmt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dmt OCA], [https://pdbe.org/2dmt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dmt RCSB], [https://www.ebi.ac.uk/pdbsum/2dmt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dmt ProSAT], [https://www.topsan.org/Proteins/RSGI/2dmt TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/BARX1_HUMAN BARX1_HUMAN]] Transcription factor, which is involved in craniofacial development, in odontogenesis and in stomach organogenesis. May have a role in the differentiation of molars from incisors. Plays a role in suppressing endodermal Wnt activity (By similarity). Binds to a regulatory module of the NCAM promoter.<ref>PMID:9804553</ref>
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[https://www.uniprot.org/uniprot/BARX1_HUMAN BARX1_HUMAN] Transcription factor, which is involved in craniofacial development, in odontogenesis and in stomach organogenesis. May have a role in the differentiation of molars from incisors. Plays a role in suppressing endodermal Wnt activity (By similarity). Binds to a regulatory module of the NCAM promoter.<ref>PMID:9804553</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Inoue, M]]
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[[Category: Inoue M]]
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[[Category: Kigawa, T]]
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[[Category: Kigawa T]]
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[[Category: Koshiba, S]]
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[[Category: Koshiba S]]
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[[Category: Ohnishi, S]]
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[[Category: Ohnishi S]]
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[[Category: Structural genomic]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S]]
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[[Category: Yoneyama M]]
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[[Category: Yoneyama, M]]
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[[Category: Dna binding protein]]
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[[Category: Homeobox domain]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Rsgi]]
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[[Category: Three helices with the dna binding helix-turn-helix motif]]
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Current revision

Solution structure of the homeobox domain of Homeobox protein BarH-like 1

PDB ID 2dmt

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