2e6f
From Proteopedia
(Difference between revisions)
| (One intermediate revision not shown.) | |||
| Line 3: | Line 3: | ||
<StructureSection load='2e6f' size='340' side='right'caption='[[2e6f]], [[Resolution|resolution]] 1.26Å' scene=''> | <StructureSection load='2e6f' size='340' side='right'caption='[[2e6f]], [[Resolution|resolution]] 1.26Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2e6f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2e6f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E6F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E6F FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.26Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene>, <scene name='pdbligand=OXC:OXONIC+ACID'>OXC</scene></td></tr> |
| - | + | ||
| - | < | + | |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e6f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e6f OCA], [https://pdbe.org/2e6f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e6f RCSB], [https://www.ebi.ac.uk/pdbsum/2e6f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e6f ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e6f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e6f OCA], [https://pdbe.org/2e6f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e6f RCSB], [https://www.ebi.ac.uk/pdbsum/2e6f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e6f ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/PYRD_TRYCC PYRD_TRYCC] Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor. Molecular oxygen can replace fumarate in vitro. | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 17: | Line 15: | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e6/2e6f_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e6/2e6f_consurf.spt"</scriptWhenChecked> | ||
| - | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> |
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| Line 28: | Line 26: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Trypanosoma cruzi]] |
| - | [[Category: Aoki | + | [[Category: Aoki T]] |
| - | [[Category: Harada | + | [[Category: Harada S]] |
| - | [[Category: Inaoka | + | [[Category: Inaoka DK]] |
| - | [[Category: Kita | + | [[Category: Kita K]] |
| - | [[Category: Kurisu | + | [[Category: Kurisu G]] |
| - | [[Category: Nara | + | [[Category: Nara T]] |
| - | [[Category: Sakamoto | + | [[Category: Sakamoto K]] |
| - | [[Category: Shiba | + | [[Category: Shiba T]] |
| - | [[Category: Shimizu | + | [[Category: Shimizu H]] |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with oxonate
| |||||||||||
Categories: Large Structures | Trypanosoma cruzi | Aoki T | Harada S | Inaoka DK | Kita K | Kurisu G | Nara T | Sakamoto K | Shiba T | Shimizu H
