Polyhedrin

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== Structural highlights ==
== Structural highlights ==
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The biological assembly of Polyhedrin is <scene name='87/873252/Cv/2'>homotrimer</scene> (PDB code [[4s1k]]). Nucleoside triphosphates stabilize polyhedrin by forming hydrogen bonds with Ser and Arg side chains of 2 monomers<ref>PMID:25751308</ref>.
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The biological assembly of ''Uranotaenia sapphirina'' cypovirus Polyhedrin is <scene name='87/873252/Cv/2'>homotrimer</scene> (PDB code [[4s1k]]). <scene name='87/873252/Cv/9'>ATP binding site</scene><ref>PMID:25751308</ref>. Water molecules are shown as red spheres. <scene name='87/873252/Cv/10'>Mg coordination site</scene>.
</StructureSection>
</StructureSection>
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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{{#tree:id=OrganizedByTopic|openlevels=0|
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*Polyhedrin
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**[[3jvb]] – PH – wiseana signata nucleopolyhedrovirus<br />
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**[[2wux]], [[2wuy]], [[3jw6]] – PH – autographa californica nucleopolyhedrovirus<br />
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**[[5gqk]], [[5yha]], [[5yhb]], [[7xhr]], [[7xws]] – bmcvPH – bombyx mori cypovirus<br />
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**[[5a9b]], [[5gqi]], [[5gqj]], [[5gqn]], [[5yr1]], [[5yr9]], [[5yra]], [[5yrb]], [[5yrc]], [[5yrd]], [[6lee]] – bmcvPH (mutant)<br />
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**[[5a8s]], [[5a8t]], [[5a9c]] – PH (mutant) – antheraea mylitta cypovirus<br />
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**[[5a8u]], [[5a8v]] – PH – orgyia pseudotsugata cypovirus<br />
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**[[5g0z]], [[5g3x]] – PH – cydia pomonella granulovirus<br />
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**[[8bbt]], [[8bc5]], [[8bck]], [[8bcl]] – PH – tipula oleracea nudivirus<br />
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*Polyhedrin complex
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**[[4s1k]], [[4s1l]], [[4zqx]] – PH + ATP – uranotaenia sapphirina cypovirus<br />
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**[[5a99]] – obcvPH + ATP – operophtera brumata cypovirus<br />
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**[[4ots]], [[4otv]], [[4x35]], [[5a9p]], [[5mqw]] – obcvPH + ATP + GTP<br />
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**[[5axv]] – bmcvPH (mutant) + CTP<br />
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**[[5gql]] – bmcvPH + ATP + CTP<br />
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**[[5axu]] – bmcvPH (mutant) + ATP + CTP<br />
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**[[2oh5]], [[2oh6]], [[2oh7]], [[5exy]], [[5exz]], [[5gqm]] – bmcvPH + ATP + GTP + CTP<br />
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**[[5a96]] – PH + GTP – lymantria dispar cypovirus<br />
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**[[5a98]] – PH + ATP – trichoplusia ni cypovirus<br />
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**[[5a9a]] – PH + UTP – simullium ubuquitum cypovirus<br />
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}}
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[[3jvb]] – PH – wiseana signata nucleopolyhedrovirus<br />
 
-
[[2wux]], [[2wuy]], [[3jw6]] – PH – autographa californica nucleopolyhedrovirus<br />
 
-
[[4s1k]], [[4s1l]], [[4zqx]] – PH + ATP – uranotaenia sapphirina cypovirus<br />
 
-
[[5a99]] – obcvPH + ATP – operophtera brumata cypovirus<br />
 
-
[[4ots]], [[4otv]], [[4x35]], [[5a9p]], [[5mqw]] – obcvPH + ATP + GTP<br />
 
-
[[5gqk]], [[5yha]], [[5yhb]] – bmcvPH – bombyx mori cypovirus<br />
 
-
[[5a9b]], [[5gqi]], [[5gqj]], [[5gqn]], [[5yr1]], [[5yr9]], [[5yra]], [[5yrb]], [[5yrc]], [[5yrd]], [[6lee]] – bmcvPH (mutant)<br />
 
-
[[5axv]] – bmcvPH (mutant) + CTP<br />
 
-
[[5gql]] – bmcvPH + ATP + CTP<br />
 
-
[[5axu]] – bmcvPH (mutant) + ATP + CTP<br />
 
-
[[2oh5]], [[2oh6]], [[2oh7]], [[5exy]], [[5exz]], [[5gqm]] – bmcvPH + ATP + GTP + CTP<br />
 
-
[[5a96]] – PH + GTP – lymantria dispar cypovirus<br />
 
-
[[5a8s]], [[5a8t]], [[5a9c]] – PH (mutant) – antheraea mylitta cypovirus<br />
 
-
[[5a98]] – PH + ATP – trichoplusia ni cypovirus<br />
 
-
[[5a9a]] – PH + UTP – simullium ubuquitum cypovirus<br />
 
-
[[5a8u]], [[5a8v]] – PH – orgyia pseudotsugata cypovirus<br />
 
-
[[5g3x]] – PH – cydia pomonella granulovirus<br />
 
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

Polyhedrin complex with ATP (PDB code 4s1k)

Drag the structure with the mouse to rotate

3D structures of polyhedrin

Updated on 04-September-2023

References

  1. Rohrmann GF. Polyhedrin structure. J Gen Virol. 1986 Aug;67 ( Pt 8):1499-513. doi: 10.1099/0022-1317-67-8-1499. PMID:3525744 doi:http://dx.doi.org/10.1099/0022-1317-67-8-1499
  2. Kunimi Y. Current status and prospects on microbial control in Japan. J Invertebr Pathol. 2007 Jul;95(3):181-6. doi: 10.1016/j.jip.2007.03.007. Epub, 2007 Mar 25. PMID:17462666 doi:http://dx.doi.org/10.1016/j.jip.2007.03.007
  3. Ginn HM, Messerschmidt M, Ji X, Zhang H, Axford D, Gildea RJ, Winter G, Brewster AS, Hattne J, Wagner A, Grimes JM, Evans G, Sauter NK, Sutton G, Stuart DI. Structure of CPV17 polyhedrin determined by the improved analysis of serial femtosecond crystallographic data. Nat Commun. 2015 Mar 9;6:6435. doi: 10.1038/ncomms7435. PMID:25751308 doi:http://dx.doi.org/10.1038/ncomms7435

Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Michal Harel

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