2eh8

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<StructureSection load='2eh8' size='340' side='right'caption='[[2eh8]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
<StructureSection load='2eh8' size='340' side='right'caption='[[2eh8]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2eh8]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EH8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EH8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2eh8]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepatitis_B_virus Hepatitis B virus] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EH8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EH8 FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2eh7|2eh7]]</div></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HUMANIZED KR127 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eh8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eh8 OCA], [https://pdbe.org/2eh8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eh8 RCSB], [https://www.ebi.ac.uk/pdbsum/2eh8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eh8 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eh8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eh8 OCA], [https://pdbe.org/2eh8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eh8 RCSB], [https://www.ebi.ac.uk/pdbsum/2eh8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eh8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/Q2EID8_HBV Q2EID8_HBV]] The middle envelope protein plays an important role in the budding of the virion. It is involved in the induction of budding in a nucleocapsid independent way. In this process the majority of envelope proteins bud to form subviral lipoprotein particles of 22 nm of diameter that do not contain a nucleocapsid (By similarity).[SAAS:SAAS000349_004_055156]
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[https://www.uniprot.org/uniprot/Q2EID8_HBV Q2EID8_HBV] The middle envelope protein plays an important role in the budding of the virion. It is involved in the induction of budding in a nucleocapsid independent way. In this process the majority of envelope proteins bud to form subviral lipoprotein particles of 22 nm of diameter that do not contain a nucleocapsid (By similarity).[SAAS:SAAS000349_004_055156]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eh/2eh8_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eh/2eh8_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Hepatitis B virus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lk3 transgenic mice]]
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[[Category: Mus musculus]]
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[[Category: Chi, S W]]
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[[Category: Chi S-W]]
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[[Category: Hong, H J]]
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[[Category: Hong HJ]]
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[[Category: Kim, S J]]
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[[Category: Kim S-J]]
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[[Category: Maeng, C Y]]
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[[Category: Maeng C-Y]]
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[[Category: Ryu, S E]]
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[[Category: Ryu S-E]]
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[[Category: Hepatitis b virus]]
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[[Category: Humanized antibody]]
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[[Category: Immune system]]
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[[Category: Monoclonal antibody]]
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[[Category: Neutralization]]
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[[Category: Pres1]]
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Current revision

Crystal structure of the complex of humanized KR127 fab and PRES1 peptide epitope

PDB ID 2eh8

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

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