2ex6

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Current revision (09:06, 6 November 2024) (edit) (undo)
 
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<StructureSection load='2ex6' size='340' side='right'caption='[[2ex6]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='2ex6' size='340' side='right'caption='[[2ex6]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2ex6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EX6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EX6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2ex6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EX6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EX6 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AIX:(2R,4S)-2-[(1R)-1-{[(2R)-2-AMINO-2-PHENYLACETYL]AMINO}-2-OXOETHYL]-5,5-DIMETHYL-1,3-THIAZOLIDINE-4-CARBOXYLIC+ACID'>AIX</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2ex2|2ex2]], [[2ex8|2ex8]], [[2ex9|2ex9]], [[2exa|2exa]], [[2exb|2exb]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AIX:(2R,4S)-2-[(1R)-1-{[(2R)-2-AMINO-2-PHENYLACETYL]AMINO}-2-OXOETHYL]-5,5-DIMETHYL-1,3-THIAZOLIDINE-4-CARBOXYLIC+ACID'>AIX</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dacB ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ex6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ex6 OCA], [https://pdbe.org/2ex6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ex6 RCSB], [https://www.ebi.ac.uk/pdbsum/2ex6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ex6 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ex6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ex6 OCA], [https://pdbe.org/2ex6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ex6 RCSB], [https://www.ebi.ac.uk/pdbsum/2ex6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ex6 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/DACB_ECOLI DACB_ECOLI]] Not involved in transpeptidation but exclusively catalyzes a DD-carboxypeptidase and DD-endopeptidase reaction.<ref>PMID:2046551</ref>
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[https://www.uniprot.org/uniprot/DACB_ECOLI DACB_ECOLI] Not involved in transpeptidation but exclusively catalyzes a DD-carboxypeptidase and DD-endopeptidase reaction.<ref>PMID:2046551</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ex/2ex6_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ex/2ex6_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus coli migula 1895]]
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[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Kishida, H]]
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[[Category: Kishida H]]
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[[Category: Lloyd, A]]
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[[Category: Lloyd A]]
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[[Category: Park, S Y]]
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[[Category: Park S-Y]]
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[[Category: Roper, D I]]
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[[Category: Roper DI]]
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[[Category: Tame, J R.H]]
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[[Category: Tame JRH]]
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[[Category: Unzai, S]]
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[[Category: Unzai S]]
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[[Category: Ampicillin]]
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[[Category: Cephem]]
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[[Category: D-alanyl-d-alanine-carboxypeptidase]]
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[[Category: D-alanyl-d-alanine-endopeptidase]]
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[[Category: Hydrolase]]
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[[Category: Penem]]
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[[Category: Penicillin-binding protein]]
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Current revision

Crystal structure of penicillin binding protein 4 (dacB) from Escherichia coli, complexed with ampicillin

PDB ID 2ex6

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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