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7ngi
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound== | |
| + | <StructureSection load='7ngi' size='340' side='right'caption='[[7ngi]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[7ngi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7NGI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7NGI FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=U9T:~{N}-[2-(2-fluorophenyl)ethyl]-4-methyl-piperidine-1-carboxamide'>U9T</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ngi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ngi OCA], [https://pdbe.org/7ngi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ngi RCSB], [https://www.ebi.ac.uk/pdbsum/7ngi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ngi ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ETHR_MYCTU ETHR_MYCTU] Involved in the repression of the monooxygenase EthA which is responsible of the formation of the active metabolite of ethionamide (ETH).<ref>PMID:10869356</ref> <ref>PMID:10944230</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Tetracycline repressor protein 3D structures|Tetracycline repressor protein 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: Pohl | + | __TOC__ |
| - | [[Category: Tatum | + | </StructureSection> |
| - | [[Category: Tomlinson | + | [[Category: Large Structures]] |
| + | [[Category: Mycobacterium tuberculosis]] | ||
| + | [[Category: Pohl E]] | ||
| + | [[Category: Tatum NJ]] | ||
| + | [[Category: Tomlinson CWE]] | ||
Current revision
Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound
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