This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
7ngm
From Proteopedia
(Difference between revisions)
m (Protected "7ngm" [edit=sysop:move=sysop]) |
|||
| (One intermediate revision not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound== | |
| + | <StructureSection load='7ngm' size='340' side='right'caption='[[7ngm]], [[Resolution|resolution]] 1.76Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[7ngm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7NGM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7NGM FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.76Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UAK:4-methyl-~{N}-[(1~{R})-1-phenylethyl]piperidine-1-carboxamide'>UAK</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ngm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ngm OCA], [https://pdbe.org/7ngm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ngm RCSB], [https://www.ebi.ac.uk/pdbsum/7ngm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ngm ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ETHR_MYCTU ETHR_MYCTU] Involved in the repression of the monooxygenase EthA which is responsible of the formation of the active metabolite of ethionamide (ETH).<ref>PMID:10869356</ref> <ref>PMID:10944230</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Tetracycline repressor protein 3D structures|Tetracycline repressor protein 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: Pohl | + | __TOC__ |
| - | [[Category: Tatum | + | </StructureSection> |
| - | [[Category: Tomlinson | + | [[Category: Large Structures]] |
| + | [[Category: Mycobacterium tuberculosis]] | ||
| + | [[Category: Pohl E]] | ||
| + | [[Category: Tatum NJ]] | ||
| + | [[Category: Tomlinson CWE]] | ||
Current revision
Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound
| |||||||||||
