7ngo
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 7ngo is ON HOLD until Paper Publication Authors: Tomlinson, C.W.E., Tatum, N.J., Pohl, E. Description: Mycobacterium tuberculosis transcriptional r...) |
|||
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound== | |
| + | <StructureSection load='7ngo' size='340' side='right'caption='[[7ngo]], [[Resolution|resolution]] 2.37Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[7ngo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7NGO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7NGO FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.37Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UAQ:~{N}-(furan-2-ylmethyl)-4-methyl-piperidine-1-carboxamide'>UAQ</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ngo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ngo OCA], [https://pdbe.org/7ngo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ngo RCSB], [https://www.ebi.ac.uk/pdbsum/7ngo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ngo ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ETHR_MYCTU ETHR_MYCTU] Involved in the repression of the monooxygenase EthA which is responsible of the formation of the active metabolite of ethionamide (ETH).<ref>PMID:10869356</ref> <ref>PMID:10944230</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Tetracycline repressor protein 3D structures|Tetracycline repressor protein 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: Pohl | + | __TOC__ |
| - | [[Category: Tatum | + | </StructureSection> |
| - | [[Category: Tomlinson | + | [[Category: Large Structures]] |
| + | [[Category: Mycobacterium tuberculosis]] | ||
| + | [[Category: Pohl E]] | ||
| + | [[Category: Tatum NJ]] | ||
| + | [[Category: Tomlinson CWE]] | ||
Current revision
Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound
| |||||||||||
