7lku
From Proteopedia
(Difference between revisions)
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
==1.65 A resolution structure of SARS-CoV-2 3CL protease in complex with inhibitor 3b (deuterated analog of inhibitor 2a)== | ==1.65 A resolution structure of SARS-CoV-2 3CL protease in complex with inhibitor 3b (deuterated analog of inhibitor 2a)== | ||
| - | <StructureSection load='7lku' size='340' side='right'caption='[[7lku]]' scene=''> | + | <StructureSection load='7lku' size='340' side='right'caption='[[7lku]], [[Resolution|resolution]] 1.65Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7LKU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7LKU FirstGlance]. <br> | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7LKU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7LKU FirstGlance]. <br> | ||
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lku FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lku OCA], [https://pdbe.org/7lku PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lku RCSB], [https://www.ebi.ac.uk/pdbsum/7lku PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lku ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=Y4D:(1R,2S)-2-((S)-2-(((((1R,3s,5S)-bicyclo[3.3.1]nonan-3-yl)methoxy)carbonyl)amino)-4-methylpentanamido)-1-hydroxy-3-((S)-2-oxopyrrolidin-3-yl)propane-1-sulfonic+acid'>Y4D</scene>, <scene name='pdbligand=Y5S:(1S,2S)-2-((S)-2-(((((1R,3s,5S)-bicyclo[3.3.1]nonan-3-yl)methoxy)carbonyl)amino)-4-methylpentanamido)-1-hydroxy-3-((S)-2-oxopyrrolidin-3-yl)propane-1-sulfonic+acid'>Y5S</scene>, <scene name='pdbligand=Y8Y:(1R,2S)-2-((S)-2-(((((1R,3r,5S)-bicyclo[3.3.1]nonan-3-yl)methoxy)carbonyl)amino)-4-methylpentanamido)-1-hydroxy-3-((S)-2-oxopyrrolidin-3-yl)propane-1-sulfonic+acid'>Y8Y</scene>, <scene name='pdbligand=Y91:(1S,2S)-2-((S)-2-(((((1R,3r,5S)-bicyclo[3.3.1]nonan-3-yl)methoxy)carbonyl)amino)-4-methylpentanamido)-1-hydroxy-3-((S)-2-oxopyrrolidin-3-yl)propane-1-sulfonic+acid'>Y91</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lku FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lku OCA], [https://pdbe.org/7lku PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lku RCSB], [https://www.ebi.ac.uk/pdbsum/7lku PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lku ProSAT]</span></td></tr> | ||
</table> | </table> | ||
__TOC__ | __TOC__ | ||
Current revision
1.65 A resolution structure of SARS-CoV-2 3CL protease in complex with inhibitor 3b (deuterated analog of inhibitor 2a)
| |||||||||||
Categories: Large Structures | Baird MA | Battaile KP | Chamandi SD | Chang KO | Groutas WC | Kashipathy MM | Kim Y | Lovell S | Nguyen HN | Rathnayake AD | Shadipeni N
