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1gsz
From Proteopedia
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<StructureSection load='1gsz' size='340' side='right'caption='[[1gsz]], [[Resolution|resolution]] 2.80Å' scene=''> | <StructureSection load='1gsz' size='340' side='right'caption='[[1gsz]], [[Resolution|resolution]] 2.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1gsz]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[1gsz]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Alicyclobacillus_acidocaldarius Alicyclobacillus acidocaldarius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GSZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GSZ FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C8E:(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE'>C8E</scene>, <scene name='pdbligand=R71:[4-({6-[ALLYL(METHYL)AMINO]HEXYL}OXY)-2-FLUOROPHENYL](4-BROMOPHENYL)METHANONE'>R71</scene></td></tr> |
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gsz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gsz OCA], [https://pdbe.org/1gsz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gsz RCSB], [https://www.ebi.ac.uk/pdbsum/1gsz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gsz ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gsz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gsz OCA], [https://pdbe.org/1gsz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gsz RCSB], [https://www.ebi.ac.uk/pdbsum/1gsz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gsz ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SQHC_ALIAD SQHC_ALIAD] Catalyzes the cyclization of squalene into hopene. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Alicyclobacillus acidocaldarius]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | + | [[Category: Lenhart A]] | |
| - | [[Category: Lenhart | + | [[Category: Pleschke AEW]] |
| - | [[Category: Pleschke | + | [[Category: Schulz GE]] |
| - | [[Category: Schulz | + | [[Category: Weihofen WA]] |
| - | [[Category: Weihofen | + | |
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Current revision
Crystal Structure of a Squalene Cyclase in Complex with the Potential Anticholesteremic Drug Ro48-8071
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