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5-hydroxytryptamine receptor 3D structures
From Proteopedia
(Difference between revisions)
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} - For a general description of the protein see [[5-hydroxytryptamine receptor]] | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} - For a general description of the protein see [[5-hydroxytryptamine receptor]] | ||
{{#tree:id=OrganizedByTopic|openlevels=0| | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
| + | |||
| + | *5-HT 1A | ||
| + | |||
| + | **[[7e2z]] – hHT1A/ cytochrome b562 (mutant) + guanine nucleotide-binding protein – Cryo EM <br /> | ||
| + | **[[7e2y]] – hHT1A/ cytochrome b562 (mutant) + guanine nucleotide-binding protein + serotonin– Cryo EM <br /> | ||
*5-HT 1B | *5-HT 1B | ||
| - | **[[ | + | **[[4iaq]], [[4iar]], [[5v54]] – hHT1B/cytochrome b562 (mutant) + drug - human<br /> |
| - | + | ||
| - | + | ||
**[[7c61]] – hHT1B/cytochrome b562 (mutant) + antibody <br /> | **[[7c61]] – hHT1B/cytochrome b562 (mutant) + antibody <br /> | ||
**[[6g79]] – hHT1B + guanine nucleotide-binding protein<br /> | **[[6g79]] – hHT1B + guanine nucleotide-binding protein<br /> | ||
| + | |||
| + | *5-HT 1D | ||
| + | |||
| + | **[[7e32]] – hHT1D + guanine nucleotide-binding protein + Scfv + serotonin – Cryo EM <br /> | ||
| + | |||
| + | *5-HT 1F | ||
| + | |||
| + | **[[7exd]] – hHT1F + guanine nucleotide-binding protein + Scfv + drug – Cryo EM <br /> | ||
*5-HT 2A | *5-HT 2A | ||
| - | **[[6a93]] – hHT2A/cytochrome b562 (mutant) + | + | **[[6a93]], [[6a94]], [[7vod]], [[7voe]], [[7wc5]], [[7wc7]], [[7wc8]], [[7wc9]] – hHT2A/cytochrome b562 (mutant) + drug<br /> |
| - | **[[ | + | **[[7wc4]] – hHT2A/cytochrome b562 (mutant) + serotonin<br /> |
| + | **[[7wc6]] – hHT2A/cytochrome b562 (mutant) + LSD<br /> | ||
**[[6wgt]] – hHT2A/cytochrome b562 + hallucinogen <br /> | **[[6wgt]] – hHT2A/cytochrome b562 + hallucinogen <br /> | ||
**[[6wh4]] – hHT2A/cytochrome b562 + agonist<br /> | **[[6wh4]] – hHT2A/cytochrome b562 + agonist<br /> | ||
| + | **[[7ran]] – hHT2A + guanine nucleotide-binding protein + Scfv + agonist – Cryo EM <br /> | ||
*5-HT 2B | *5-HT 2B | ||
**[[4nc3]] – hHT2B/cytochrome b562 (mutant) <br /> | **[[4nc3]] – hHT2B/cytochrome b562 (mutant) <br /> | ||
| - | **[[4ib4]] – hHT2B/cytochrome b562 (mutant) + | + | **[[4ib4]] – hHT2B/cytochrome b562 (mutant) + drug <br /> |
**[[5tvn]] – hHT2B/cytochrome b562 (mutant) + LSD <br /> | **[[5tvn]] – hHT2B/cytochrome b562 (mutant) + LSD <br /> | ||
**[[5tud]] – hHT2B/cytochrome b562 (mutant) + antibody <br /> | **[[5tud]] – hHT2B/cytochrome b562 (mutant) + antibody <br /> | ||
| Line 28: | Line 41: | ||
*5-HT 2C | *5-HT 2C | ||
| - | **[[6bqg]] | + | **[[6bqg]], [[6bqh]] – hHT2C/cytochrome b562 (mutant) + ergotamine <br /> |
| - | + | ||
*5-HT 3A | *5-HT 3A | ||
| Line 39: | Line 51: | ||
**[[6dg7]], [[6dg8]], [[6hin]], [[6hio]], [[6hiq]] – mHT3A + serotonin – Cryo EM<br /> | **[[6dg7]], [[6dg8]], [[6hin]], [[6hio]], [[6hiq]] – mHT3A + serotonin – Cryo EM<br /> | ||
**[[6y59]], [[6y5a]], [[6y5b]] – mHT3A (mutant) + serotonin – Cryo EM<br /> | **[[6y59]], [[6y5a]], [[6y5b]] – mHT3A (mutant) + serotonin – Cryo EM<br /> | ||
| + | |||
| + | *5-HT 4 | ||
| + | |||
| + | **[[7xt9]], [[7xta]] – hHT4 + guanine nucleotide-binding protein + serotonin – Cryo EM <br /> | ||
| + | **[[7xt8]] – hHT4 + guanine nucleotide-binding protein + nanobody + serotonin – Cryo EM <br /> | ||
| + | |||
| + | *5-HT 5A | ||
| + | |||
| + | **[[7um5]], [[7um6]], [[7um7]] – hHT5A + minigo + guanine nucleotide-binding protein + scFv + drug – Cryo EM <br /> | ||
| + | **[[7um4]] – hHT5A + PGS + quinolone derivative <br /> | ||
| + | |||
| + | *5-HT 6 | ||
| + | |||
| + | **[[7xtb]] – hHT6 + guanine nucleotide-binding protein + nanobody + serotonin – Cryo EM <br /> | ||
| + | |||
}} | }} | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Current revision
3D structures of 5-hydroxytryptamine receptor
Updated on 11-August-2022 - For a general description of the protein see 5-hydroxytryptamine receptor
