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5-hydroxytryptamine receptor 3D structures

From Proteopedia

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Current revision (10:24, 11 August 2022) (edit) (undo)
 
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} - For a general description of the protein see [[5-hydroxytryptamine receptor]]
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} - For a general description of the protein see [[5-hydroxytryptamine receptor]]
{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|
 +
 +
*5-HT 1A
 +
 +
**[[7e2z]] – hHT1A/ cytochrome b562 (mutant) + guanine nucleotide-binding protein – Cryo EM <br />
 +
**[[7e2y]] – hHT1A/ cytochrome b562 (mutant) + guanine nucleotide-binding protein + serotonin– Cryo EM <br />
*5-HT 1B
*5-HT 1B
-
**[[4iar]] – hHT1B/cytochrome b562 (mutant) + ergotamine - human<br />
+
**[[4iaq]], [[4iar]], [[5v54]] – hHT1B/cytochrome b562 (mutant) + drug - human<br />
-
**[[4iaq]] – hHT1B/cytochrome b562 (mutant) + hydroergotamine <br />
+
-
**[[5v54]] – hHT1B/cytochrome b562 (mutant) + methiothepin <br />
+
**[[7c61]] – hHT1B/cytochrome b562 (mutant) + antibody <br />
**[[7c61]] – hHT1B/cytochrome b562 (mutant) + antibody <br />
**[[6g79]] – hHT1B + guanine nucleotide-binding protein<br />
**[[6g79]] – hHT1B + guanine nucleotide-binding protein<br />
 +
 +
*5-HT 1D
 +
 +
**[[7e32]] – hHT1D + guanine nucleotide-binding protein + Scfv + serotonin – Cryo EM <br />
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 +
*5-HT 1F
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 +
**[[7exd]] – hHT1F + guanine nucleotide-binding protein + Scfv + drug – Cryo EM <br />
*5-HT 2A
*5-HT 2A
-
**[[6a93]] – hHT2A/cytochrome b562 (mutant) + risperidone <br />
+
**[[6a93]], [[6a94]], [[7vod]], [[7voe]], [[7wc5]], [[7wc7]], [[7wc8]], [[7wc9]] – hHT2A/cytochrome b562 (mutant) + drug<br />
-
**[[6a94]] – hHT2A/cytochrome b562 (mutant) + zotepine <br />
+
**[[7wc4]] – hHT2A/cytochrome b562 (mutant) + serotonin<br />
 +
**[[7wc6]] – hHT2A/cytochrome b562 (mutant) + LSD<br />
**[[6wgt]] – hHT2A/cytochrome b562 + hallucinogen <br />
**[[6wgt]] – hHT2A/cytochrome b562 + hallucinogen <br />
**[[6wh4]] – hHT2A/cytochrome b562 + agonist<br />
**[[6wh4]] – hHT2A/cytochrome b562 + agonist<br />
 +
**[[7ran]] – hHT2A + guanine nucleotide-binding protein + Scfv + agonist – Cryo EM <br />
*5-HT 2B
*5-HT 2B
**[[4nc3]] – hHT2B/cytochrome b562 (mutant) <br />
**[[4nc3]] – hHT2B/cytochrome b562 (mutant) <br />
-
**[[4ib4]] – hHT2B/cytochrome b562 (mutant) + ergotamine <br />
+
**[[4ib4]] – hHT2B/cytochrome b562 (mutant) + drug <br />
**[[5tvn]] – hHT2B/cytochrome b562 (mutant) + LSD <br />
**[[5tvn]] – hHT2B/cytochrome b562 (mutant) + LSD <br />
**[[5tud]] – hHT2B/cytochrome b562 (mutant) + antibody <br />
**[[5tud]] – hHT2B/cytochrome b562 (mutant) + antibody <br />
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*5-HT 2C
*5-HT 2C
-
**[[6bqg]] – hHT2C/cytochrome b562 (mutant) + ergotamine <br />
+
**[[6bqg]], [[6bqh]] – hHT2C/cytochrome b562 (mutant) + ergotamine <br />
-
**[[6bqh]] – hHT2C/cytochrome b562 + ritanserin <br />
+
*5-HT 3A
*5-HT 3A
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**[[6dg7]], [[6dg8]], [[6hin]], [[6hio]], [[6hiq]] – mHT3A + serotonin – Cryo EM<br />
**[[6dg7]], [[6dg8]], [[6hin]], [[6hio]], [[6hiq]] – mHT3A + serotonin – Cryo EM<br />
**[[6y59]], [[6y5a]], [[6y5b]] – mHT3A (mutant) + serotonin – Cryo EM<br />
**[[6y59]], [[6y5a]], [[6y5b]] – mHT3A (mutant) + serotonin – Cryo EM<br />
 +
 +
*5-HT 4
 +
 +
**[[7xt9]], [[7xta]] – hHT4 + guanine nucleotide-binding protein + serotonin – Cryo EM <br />
 +
**[[7xt8]] – hHT4 + guanine nucleotide-binding protein + nanobody + serotonin – Cryo EM <br />
 +
 +
*5-HT 5A
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 +
**[[7um5]], [[7um6]], [[7um7]] – hHT5A + minigo + guanine nucleotide-binding protein + scFv + drug – Cryo EM <br />
 +
**[[7um4]] – hHT5A + PGS + quinolone derivative <br />
 +
 +
*5-HT 6
 +
 +
**[[7xtb]] – hHT6 + guanine nucleotide-binding protein + nanobody + serotonin – Cryo EM <br />
 +
}}
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

3D structures of 5-hydroxytryptamine receptor

Updated on 11-August-2022 - For a general description of the protein see 5-hydroxytryptamine receptor

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

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