7nlk
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 7nlk is ON HOLD Authors: Koehnke, J., Sikandar, A. Description: LasB, N-aryl-2-butylmercaptoacetamide Category: Unreleased Structures [[Categor...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==LasB, N-aryl-2-butylmercaptoacetamide== | |
| - | + | <StructureSection load='7nlk' size='340' side='right'caption='[[7nlk]], [[Resolution|resolution]] 1.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7nlk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_UCBPP-PA14 Pseudomonas aeruginosa UCBPP-PA14]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7NLK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7NLK FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=UHK:(2~{S})-4-methyl-~{N}-(4-methylphenyl)-2-sulfanyl-pentanamide'>UHK</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7nlk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7nlk OCA], [https://pdbe.org/7nlk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7nlk RCSB], [https://www.ebi.ac.uk/pdbsum/7nlk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7nlk ProSAT]</span></td></tr> |
| - | [[Category: Koehnke | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ELAS_PSEAB ELAS_PSEAB] Cleaves host elastase, collagen, IgI and several complement components as well as endogenous pro-aminopeptidase, pro-chitin-binding protein (cbpD). Cleaves its own pro-peptide. Involved in the pathogenesis of P.aeruginosa infections.[UniProtKB:P14756] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Pseudomonas aeruginosa UCBPP-PA14]] | ||
| + | [[Category: Koehnke J]] | ||
| + | [[Category: Sikandar A]] | ||
Current revision
LasB, N-aryl-2-butylmercaptoacetamide
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