6m6e

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==Solution structure of the core domain of Fibroblast growth factor 21 (FGF21)==
==Solution structure of the core domain of Fibroblast growth factor 21 (FGF21)==
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<StructureSection load='6m6e' size='340' side='right'caption='[[6m6e]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
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<StructureSection load='6m6e' size='340' side='right'caption='[[6m6e]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6m6e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6M6E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6M6E FirstGlance]. <br>
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<table><tr><td colspan='2'>Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6M6E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6M6E FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FGF21 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 10 models</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6m6e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6m6e OCA], [https://pdbe.org/6m6e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6m6e RCSB], [https://www.ebi.ac.uk/pdbsum/6m6e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6m6e ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6m6e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6m6e OCA], [https://pdbe.org/6m6e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6m6e RCSB], [https://www.ebi.ac.uk/pdbsum/6m6e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6m6e ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
 
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[[https://www.uniprot.org/uniprot/FGF21_HUMAN FGF21_HUMAN]] Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB.<ref>PMID:15902306</ref> <ref>PMID:17623664</ref>
 
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6m6e" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6m6e" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Fibroblast growth factor 3D structures|Fibroblast growth factor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Wang, J]]
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[[Category: Wang J]]
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[[Category: Zhao, H]]
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[[Category: Zhao H]]
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[[Category: Zhu, L]]
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[[Category: Zhu L]]
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[[Category: Anti-diabete]]
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[[Category: Beta-klotho binding]]
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[[Category: Beta-trefoil conformation]]
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[[Category: Hormone]]
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[[Category: Metabolic regulator]]
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Current revision

Solution structure of the core domain of Fibroblast growth factor 21 (FGF21)

PDB ID 6m6e

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