7lxd
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of yeast DNA Polymerase Zeta (apo)== | |
| + | <StructureSection load='7lxd' size='340' side='right'caption='[[7lxd]], [[Resolution|resolution]] 4.11Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[7lxd]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7LXD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7LXD FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.11Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lxd OCA], [https://pdbe.org/7lxd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lxd RCSB], [https://www.ebi.ac.uk/pdbsum/7lxd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lxd ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DPOZ_YEAST DPOZ_YEAST] Nonessential DNA polymerase. Required for DNA damage induced mutagenesis. Involved in DNA repair, mitochondrial DNA repair and translesion synthesis. Translesion synthesis in S.cerevisiae may use a specialized DNA polymerase that is not required for other DNA replicative processes. Has a role in the bypass of abasic (AP) sites. Highly inefficient in incorporating nucleotides opposite the AP site, but efficiently extends from nucleotides, particularly an A, inserted opposite the lesion.<ref>PMID:11316789</ref> <ref>PMID:16452144</ref> <ref>PMID:2676986</ref> <ref>PMID:8658138</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[DNA polymerase 3D structures|DNA polymerase 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Saccharomyces cerevisiae S288C]] |
| - | [[Category: | + | [[Category: Botuyan MV]] |
| - | [[Category: | + | [[Category: Chan K-Y]] |
| - | [[Category: | + | [[Category: Chiu P-L]] |
| - | [[Category: | + | [[Category: Craig TA]] |
| - | [[Category: Truong | + | [[Category: Cui G]] |
| + | [[Category: Kumar R]] | ||
| + | [[Category: Mer G]] | ||
| + | [[Category: Serkasevich RA]] | ||
| + | [[Category: Truong CD]] | ||
Current revision
Structure of yeast DNA Polymerase Zeta (apo)
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