2gby
From Proteopedia
(Difference between revisions)
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<StructureSection load='2gby' size='340' side='right'caption='[[2gby]], [[Resolution|resolution]] 2.90Å' scene=''> | <StructureSection load='2gby' size='340' side='right'caption='[[2gby]], [[Resolution|resolution]] 2.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2gby]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2gby]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GBY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GBY FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BRN:BERENIL'>BRN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gby FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gby OCA], [https://pdbe.org/2gby PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gby RCSB], [https://www.ebi.ac.uk/pdbsum/2gby PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gby ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gby FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gby OCA], [https://pdbe.org/2gby PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gby RCSB], [https://www.ebi.ac.uk/pdbsum/2gby PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gby ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/QACR_STAAU QACR_STAAU] Transcriptional repressor of qacA. Binds to IR1, an unusually long 28 bp operator, which is located downstream from the qacA promoter and overlaps its transcription start site. QacR is induced from its IR1 site by binding to one of many structurally dissimilar cationic lipophilic compounds, which are also substrates of QacA. | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Staphylococcus aureus]] |
| - | [[Category: | + | [[Category: Schuman JT]] |
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Current revision
Structure of QacR Multidrug Transcriptional Regulator Bound to Bivalent Diamidine Berenil
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