2gm8

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Current revision (09:43, 30 August 2023) (edit) (undo)
 
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<StructureSection load='2gm8' size='340' side='right'caption='[[2gm8]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='2gm8' size='340' side='right'caption='[[2gm8]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2gm8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrae Pyrae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GM8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GM8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2gm8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrobaculum_aerophilum_str._IM2 Pyrobaculum aerophilum str. IM2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GM8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GM8 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=HMH:4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE'>HMH</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2gm7|2gm7]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=HMH:4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE'>HMH</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tenA/thi4 (pag5_170) ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=178306 PYRAE])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Thiamine_pyridinylase Thiamine pyridinylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.2 2.5.1.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gm8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gm8 OCA], [https://pdbe.org/2gm8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gm8 RCSB], [https://www.ebi.ac.uk/pdbsum/2gm8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gm8 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gm8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gm8 OCA], [https://pdbe.org/2gm8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gm8 RCSB], [https://www.ebi.ac.uk/pdbsum/2gm8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gm8 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q8ZZM9_PYRAE Q8ZZM9_PYRAE]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Pyrae]]
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[[Category: Pyrobaculum aerophilum str. IM2]]
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[[Category: Thiamine pyridinylase]]
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[[Category: Chan S]]
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[[Category: Chan, S]]
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[[Category: Han GW]]
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[[Category: Han, G W]]
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[[Category: Pashkov I]]
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[[Category: Pashkov, I]]
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[[Category: Perry LJ]]
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[[Category: Perry, L J]]
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[[Category: Sawaya MR]]
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[[Category: Sawaya, M R]]
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[[Category: Thiaminase]]
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[[Category: Transcription]]
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[[Category: Transferase]]
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Current revision

TenA Homolog/Thi-4 Thiaminase complexed with product 4-amino-5-hydroxymethyl-2-methylpyrimidine

PDB ID 2gm8

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