Aldolase 3D structures

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{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|
-
*Fructose–1,6-bisphosphate aldolase
+
*Fructose–1,6-bisphosphate aldolase or fructose-bisphosphate aldolase
**[[1xfb]], [[1qo5]], [[2ald]], [[1ald]], [[5ky6]] – hFBPA – human<br />
**[[1xfb]], [[1qo5]], [[2ald]], [[1ald]], [[5ky6]] – hFBPA – human<br />
**[[1xdl]], [[1xdm]] – hFBPA (mutant)<br />
**[[1xdl]], [[1xdm]] – hFBPA (mutant)<br />
-
**[[1zah]], [[1fdj]], [[1ewd]], [[1ewe]], [[1ex5]], [[1ado]], [[5vy5]] - rFBPA – rabbit<br />
+
**[[8d44]] - hFBPA B – Cryo EM<br />
 +
**[[7u5j]] - bFBPA – bovine - Cryo EM<br />
 +
**[[1zah]], [[1fdj]], [[1ewd]], [[1ewe]], [[1ex5]], [[1ado]], [[5vy5]], [[7ka4]] - rFBPA – rabbit<br />
**[[3dfn]], [[3dfp]], [[3dfq]], [[3dft]], [[2bv4]], [[3b8d]], [[3bv4]], [[5f4x]] – rFBPA (mutant)<br />
**[[3dfn]], [[3dfp]], [[3dfq]], [[3dft]], [[2bv4]], [[3b8d]], [[3bv4]], [[5f4x]] – rFBPA (mutant)<br />
-
**[[6v20]] - rFBPA – Cryo EM<br />
+
**[[6v20]], [[7k9l]], [[7k9x]], [[7ka2]], [[7ka3]], [[7vdc]], [[8ehg]], [[8ew2]], [[8twk]], [[8twl]], [[8twm]] - rFBPA – Cryo EM<br />
**[[1fba]] – FBPA – ''Drosophila melanogaster''<br />
**[[1fba]] – FBPA – ''Drosophila melanogaster''<br />
**[[1ojx]], [[1ok6]] – TptFBPA – ''Thermoproteus tenax''<br />
**[[1ojx]], [[1ok6]] – TptFBPA – ''Thermoproteus tenax''<br />
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**[[5u4n]] – FBPA – ''Neisseria gonorrhoeae''<br />
**[[5u4n]] – FBPA – ''Neisseria gonorrhoeae''<br />
**[[6lnk]] – FBPA – ''Candida albicans''<br />
**[[6lnk]] – FBPA – ''Candida albicans''<br />
 +
**[[7b2n]] – FBPA – ''Chlamydomonas reinhardtii''<br />
 +
**[[7efs]] – FBPA – ''Artemisia sieversiana''<br />
*FBPA complex
*FBPA complex
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**[[3n9r]], [[3n9s]], [[3c52]], [[3c56]] - HpFBPA + inhibitor<br />
**[[3n9r]], [[3n9s]], [[3c52]], [[3c56]] - HpFBPA + inhibitor<br />
**[[3mmt]] – FBPA + FBP – ''Bartonella henselae''<br />
**[[3mmt]] – FBPA + FBP – ''Bartonella henselae''<br />
-
**[[7nc7]] – FBPA + dihydroxyacetonephosphate – ''Bacillus methanolicus''<br />
+
**[[7nc7]] – BmFBPA + dihydroxyacetonephosphate – ''Bacillus methanolicus''<br />
 +
**[[7ncc]] – BmFBPA + imidazole + succinate derivativc<br />
 +
**[[7v6g]] - CaFBPA (mutant) + inhibitor<br />
 +
**[[7v6f]] - CaFBPA (mutant) + G3P<br />
*Fructose–6-phosphate aldolase
*Fructose–6-phosphate aldolase
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**[[1l6w]], [[4s1f]] – EcF6PA 1 <br />
**[[1l6w]], [[4s1f]] – EcF6PA 1 <br />
**[[4rz4]], [[4rxg]], [[4rxf]], [[5zol]] – EcF6PA 1 (mutant)<br />
**[[4rz4]], [[4rxg]], [[4rxf]], [[5zol]] – EcF6PA 1 (mutant)<br />
 +
**[[7qxf]] – EcF6PA 1 (mutant) + ligand<br />
*Deoxyribose-phosphate aldolase
*Deoxyribose-phosphate aldolase
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**[[2a4a]] – DERA – ''Plasmodium yoelii''<br />
**[[2a4a]] – DERA – ''Plasmodium yoelii''<br />
**[[1vcv]] – DERA – ''Pyrobaculum aerophilum''<br />
**[[1vcv]] – DERA – ''Pyrobaculum aerophilum''<br />
-
**[[1p1x]], [[1ktn]], [[3npu]], [[3npv]], [[3npw]], [[3npx]], [[3nq2]], [[3nq8]], [[3nqv]], [[3nr0]], [[3q2d]], [[6z9j]] – EcDERA<br />
+
**[[1p1x]], [[1ktn]], [[3npu]], [[3npv]], [[3npw]], [[3npx]], [[3nq2]], [[3nq8]], [[3nqv]], [[3nr0]], [[3q2d]], [[6z9j]], [[7p75]] – EcDERA<br />
**[[5emu]], [[5el1]], [[5eky]], [[6z9h]] - EcDERA (mutant)<br />
**[[5emu]], [[5el1]], [[5eky]], [[6z9h]] - EcDERA (mutant)<br />
-
**[[1jcj]], [[1jcl]] – EcDERA (mutant) + reaction intermediate<br />
+
**[[1jcj]], [[1jcl]], [[7p76]] – EcDERA (mutant) + reaction intermediate<br />
**[[6z9i]] - EcDERA (mutant) + G3P<br />
**[[6z9i]] - EcDERA (mutant) + G3P<br />
**[[1n7k]] – ApDERA – ''Aeropyrum pernix''<br />
**[[1n7k]] – ApDERA – ''Aeropyrum pernix''<br />
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**[[6msw]] – BhDERA (mutant) – ''Bacillus halodurans''<br />
**[[6msw]] – BhDERA (mutant) – ''Bacillus halodurans''<br />
-
*Dihydroneopterin aldolase
+
*7,8-dihydroneopterin aldolase
**[[1sql]] – AtDHNPA + guanine <br />
**[[1sql]] – AtDHNPA + guanine <br />
**[[3r2e]] – YpDHNPA – ''Yersinia pestis''<br />
**[[3r2e]] – YpDHNPA – ''Yersinia pestis''<br />
-
**[[6ojo]] – YpDHNPA + pterin <br />
+
**[[6ojo]], [[7su4]], [[7su7]] – YpDHNPA + pterin <br />
 +
**[[7su6]] – YpDHNPA (mutant) + dihydroneopterin<br />
**[[2cg8]] – SpDHNPA – ''Streptpcoccus pneumoniae''<br />
**[[2cg8]] – SpDHNPA – ''Streptpcoccus pneumoniae''<br />
**[[2o90]] – EcDHNPA + neopterin<br />
**[[2o90]] – EcDHNPA + neopterin<br />
**[[2nm2]], [[2nm3]], [[1u68]], [[2dhn]] - SaDHNPA + neopterin<br />
**[[2nm2]], [[2nm3]], [[1u68]], [[2dhn]] - SaDHNPA + neopterin<br />
 +
**[[8su7]] – BaDHNPA <br />
**[[5f3m]] – BaDHNPA + neopterin <br />
**[[5f3m]] – BaDHNPA + neopterin <br />
 +
**[[8sv5]] – BaDHNPA + dihydropterin derivative<br />
**[[1rri]], [[1rrw]], [[1rry]], [[1rs2]], [[1rs4]], [[1rsd]], [[1rsi]], [[1dhn]] - SaDHNPA + inhibitor<br />
**[[1rri]], [[1rrw]], [[1rry]], [[1rs2]], [[1rs4]], [[1rsd]], [[1rsi]], [[1dhn]] - SaDHNPA + inhibitor<br />
**[[1z9w]] – MtDHNPA<br />
**[[1z9w]] – MtDHNPA<br />
**[[3v9o]] - DHNPA + guanine – ''Burkholderia thailandensis''<br />
**[[3v9o]] - DHNPA + guanine – ''Burkholderia thailandensis''<br />
**[[5far]] – BcDHNPA + methylguanine – ''Bacillus cereus''<br />
**[[5far]] – BcDHNPA + methylguanine – ''Bacillus cereus''<br />
-
 
+
**[[8evk]] – HpDHNPA + pterin <br />
-
*HpcH/HpaI aldolase
+
-
 
+
-
**[[3qz6]] – HPA – ''Desulfitobacterium hafniense''<br />
+
-
**[[2v5j]] – EcHPA<br />
+
-
**[[2v5k]] – EcHPA + oxamate<br />
+
-
**[[4l7z]] – CaHHALD – ''Chloroflexus aurantiacus''<br />
+
-
**[[4l80]] – CaHHALD + oxalate + propionyl-CoA<br />
+
-
**[[4mf4]] – BcHHALD - ''Burkholderia cenocepacia'' <br />
+
-
**[[6kin]] – RcHHALD – ''Roseiflexus castenholzii''<br />
+
-
**[[6kkh]] – RcHHALD + oxalate <br />
+
-
**[[6r62]] – HHALD + hydroxypyruvate – ''Sphingomonas wittichii''<br />
+
-
 
+
-
*Sialic acid aldolase
+
-
 
+
-
**[[3lbm]] – EcSAA <br />
+
-
**[[3lcf]], [[3lcg]], [[3lch]], [[3lci]], [[3lcl]], [[2wnq]], [[2wo5]] - EcSAA (mutant)<br />
+
-
**[[3lbc]] – EcSAA + L-arabinose<br />
+
-
**[[2wnn]] – EcSAA + pyruvate <br />
+
-
**[[2wnz]], [[2wkj]] - EcSAA (mutant) + pyruvate <br />
+
-
**[[2wpb]] - EcSAA (mutant) + pyruvate + inhibitor<br />
+
-
**[[3lcx]] - EcSAA L-KDO (mutant)<br />
+
-
**[[3lcw]] - EcSAA L-KDO (mutant) + hydroxypyruvate <br />
+
*Oxoadipate aldolase
*Oxoadipate aldolase
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**[[3noj]] – PpCHA-ALD – ''Pseudomonas putida''<br />
**[[3noj]] – PpCHA-ALD – ''Pseudomonas putida''<br />
-
*Oxovalerate aldolase
+
*4-hydroxy-2-oxovalerate aldolase
-
**[[1nvm]] – OVA + acetaldehyde dehydrogenase - ''Pseudomonas''<br />
+
**[[1nvm]], [[8ix7]] – OVA + acetaldehyde dehydrogenase - ''Pseudomonas''<br />
**[[4jn6]] – MtOVA + acetaldehyde dehydrogenase<br />
**[[4jn6]] – MtOVA + acetaldehyde dehydrogenase<br />
**[[4lrs]], [[4lrt]] – OVA + acetaldehyde dehydrogenase – ''Thermomonospora curvata''<br />
**[[4lrs]], [[4lrt]] – OVA + acetaldehyde dehydrogenase – ''Thermomonospora curvata''<br />
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**[[1fwr]] - EcKDPG (mutant)<br />
**[[1fwr]] - EcKDPG (mutant)<br />
**[[5xse]] - ZmKDPG – ''Zymomonas mobilis''<br />
**[[5xse]] - ZmKDPG – ''Zymomonas mobilis''<br />
 +
**[[8di1]] - KDPG – ''Tannerella forsythia''<br />
*KDPG complex
*KDPG complex
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**[[2yda]] – KDG – ''Vibrio fischeri''
**[[2yda]] – KDG – ''Vibrio fischeri''
-
*Deoxyphosphooctonate aldolase
+
*Deoxyphosphooctonate aldolase or 2-dehydro-3-deoxy-6-phosphooctonate aldolase
**See [[Kdo-8-phosphate synthase]]
**See [[Kdo-8-phosphate synthase]]
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**[[6bdd]] – KaALD + heme – ''Kordia algicida''<br />
**[[6bdd]] – KaALD + heme – ''Kordia algicida''<br />
**[[6bde]] – KaALD (mutant) + heme <br />
**[[6bde]] – KaALD (mutant) + heme <br />
 +
 +
*Sulfofructosephosphate aldolase
 +
 +
**[[7ag7]] – SeSFP – ''Salmonella enterica''<br />
 +
**[[7ne2]] – SeSFP +SFP/DHAP <br />
 +
**[[7ag1]] – EcSFP <br />
 +
**[[8q59]] – YaSFP + sulfofructose phosphate – ''Yersinia aldovae''<br />
 +
**[[8q57]] – YaSFP + sulfate<br />
*Phospho-2-dehydro-3-deoxyheptonate aldolase
*Phospho-2-dehydro-3-deoxyheptonate aldolase
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**[[3ocr]] – ALDII – ''Pseudomonas syringae''<br />
**[[3ocr]] – ALDII – ''Pseudomonas syringae''<br />
 +
**[[7v8t]] – ALDII – ''Pseudomonas aeruginosa''<br />
**[[2vws]] – EcALDII<br />
**[[2vws]] – EcALDII<br />
**[[2vwt]] – EcALDII + pyruvate <br />
**[[2vwt]] – EcALDII + pyruvate <br />
 +
**[[8q5a]] – ALDII + DHAP – ''Hafnia paralvei''<br />
*Fructose–1,6-bisphosphate aldolase
*Fructose–1,6-bisphosphate aldolase
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**[[6btd]] – BtFPA – ''Bacillus thuringiensis''<br />
**[[6btd]] – BtFPA – ''Bacillus thuringiensis''<br />
**[[6btg]] – BtFPA + DHAP <br />
**[[6btg]] – BtFPA + DHAP <br />
 +
**[[7x78]] – FPA – ''Klebsiella pneumoniae''<br />
 +
 +
*HpcH/HpaI aldolase or 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase or Metal-dependent pyruvate aldolase
 +
 +
**[[3qz6]] – HPA – ''Desulfitobacterium hafniense''
 +
**[[2v5j]] – EcHPA
 +
**[[2v5k]] – EcHPA + oxamate
 +
**[[4l7z]] – CaHHALD – ''Chloroflexus aurantiacus''<br />
 +
**[[4l80]] – CaHHALD + oxalate + propionyl-CoA<br />
 +
**[[4mf4]] – BcHHALD - ''Burkholderia cenocepacia'' <br />
 +
**[[6kin]] – RcHHALD – ''Roseiflexus castenholzii''<br />
 +
**[[6kkh]] – RcHHALD + oxalate <br />
 +
**[[7nuj]], [[7o5i]], [[7o5r]] – SwHHALD – ''Sphingomonas wittichii''<br />
 +
**[[7nr1]], [[7o5w]], [[7o9r]], [[7obu]] - SwHHALD (mutant)<br />
 +
**[[6r62]] – SwHHALD + hydroxypyruvate <br />
 +
**[[7o5v]], [[7o87]] – SwHHALD (mutant) + hydroxypyruvate <br />
 +
**[[8adq]] – SwHHALD + hydroxypyruvate + glyceraldehyde<br />
 +
**[[4b5x]] – EcPyrA (mutant)
 +
**[[4b5s]] – EcPyrA + pyruvate + Co + Mg
 +
**[[4b5w]] – EcPyrA (mutant) + pyruvate + Co
 +
**[[4b5t]] – EcPyrA + keto-butyrate + Co + Mg
 +
**[[4b5u]] – EcPyrA + succinic semialdehyde + Co + Mg
 +
**[[4b5v]] – EcPyrA + pyruvate + heptanedioate derivative + Mg
 +
**[[tet8]] – AbHpai + Ca <br />
 +
**[[7etd]] – AbHpai + Ca + Zn<br />
 +
**[[7ete]] – AbHpai + Ca + Mg<br />
 +
**[[7etb]], [[7etf]] – AbHpai + pyruvate + Ca + Mn<br />
 +
**[[7et9]], [[7eta]], [[7etc]], [[7etg]], [[7eth]], [[7eti]] – AbHpai + pyruvate + Ca + Zn<br />
*Sphingosine-1-phosphate Aldolase or Sphingosine-1-phosphate lyase
*Sphingosine-1-phosphate Aldolase or Sphingosine-1-phosphate lyase
-
**[[3mc6]] – ySCDPL1 (mutant) <br />
 
**[[4q6r]] – hSPL + inhibitor<br />
**[[4q6r]] – hSPL + inhibitor<br />
 +
**[[8ayf]] – hSPL + PLP derivative<br />
 +
**[[3mc6]] – ySCDPL1 (mutant) <br />
*Rhamnulose-1-phosphate aldolase
*Rhamnulose-1-phosphate aldolase
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**[[6qkb]] – HAspA – ''Paracoccus dentrificuans''<br />
**[[6qkb]] – HAspA – ''Paracoccus dentrificuans''<br />
-
*Threonine aldolase
+
*L-Threonine aldolase
 +
**[[8pum]], [[8pus]] – mL-ThrA - mouse<br />
**[[2fm1]], [[1m6s]], [[1jg8]] – TmThrA<br />
**[[2fm1]], [[1m6s]], [[1jg8]] – TmThrA<br />
**[[1lw4]], [[1lw5]] – TmThrA + amino acid<br />
**[[1lw4]], [[1lw5]] – TmThrA + amino acid<br />
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**[[3wgb]] – AjThrA – ''Aeromonas jandaei''<br />
**[[3wgb]] – AjThrA – ''Aeromonas jandaei''<br />
**[[3wgc]] – AjThrA (mutant)<br />
**[[3wgc]] – AjThrA (mutant)<br />
-
**[[4v15]] – ThrA – ''Achromobacter xylosoxidans''<br />
 
**[[5vye]] – PpThrA + pyridoxime derivative<br />
**[[5vye]] – PpThrA + pyridoxime derivative<br />
**[[7k34]] – ThrA – ''Pseudomonas fluorescens''<br />
**[[7k34]] – ThrA – ''Pseudomonas fluorescens''<br />
 +
**[[7w0i]] – L-ThrA – Mycobacterium vanbaalenii<br />
 +
**[[7yvr]] – L-ThrA – Neptunomonas marina<br />
 +
 +
*D-threonine aldolase
 +
 +
**[[7yqa]] – CrD-ThrA<br />
 +
**[[4v15]] – D-ThrA – ''Achromobacter xylosoxidans''<br />
*Phenylserine aldolase
*Phenylserine aldolase
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**[[1v72]] – PpFSA<br />
**[[1v72]] – PpFSA<br />
**[[1j2w]], [[1ub3]] - TtALD<br />
**[[1j2w]], [[1ub3]] - TtALD<br />
- 
-
*Metal-dependent pyruvate aldolase 2
 
- 
-
**[[4b5x]] – EcPyrA (mutant)<br />
 
-
**[[4b5s]] – EcPyrA + pyruvate + Co + Mg<br />
 
-
**[[4b5w]] – EcPyrA (mutant) + pyruvate + Co <br />
 
-
**[[4b5t]] – EcPyrA + keto-butyrate + Co + Mg<br />
 
-
**[[4b5u]] – EcPyrA + succinic semialdehyde + Co + Mg<br />
 
-
**[[4b5v]] – EcPyrA + pyruvate + heptanedioate derivative + Mg
 
*Retro-aldolase
*Retro-aldolase
-
**[[3b5l]], [[3hoj]], [[3nxf]], [[3o6y]], [[3ud6]], [[4a29]], [[4pek]], [[4pej]], [[4pa8]] – RA – artificial gene<br />
+
**[[3b5l]], [[3hoj]], [[3nxf]], [[3o6y]], [[3ud6]], [[4a29]], [[4pek]], [[4pej]], [[4pa8]], [[7f1i]], [[7f1j]], [[7f1k]], [[7f1l]] – RA – artificial gene<br />
**[[4ou1]], [[4a2r]], [[4a2s]], [[4pa8]], [[5aou]], [[6tfa]] – SsRA<br />
**[[4ou1]], [[4a2r]], [[4a2s]], [[4pa8]], [[5aou]], [[6tfa]] – SsRA<br />
**[[5an7]] – SsRA + inhibitor<br />
**[[5an7]] – SsRA + inhibitor<br />
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*17-alpha-hydroxyprogesterone aldolase (steroid 17-alpha-hydroxylase /17,20 lyase) see [[Cytochrome P450]]
*17-alpha-hydroxyprogesterone aldolase (steroid 17-alpha-hydroxylase /17,20 lyase) see [[Cytochrome P450]]
 +
 +
*Sialic acid aldolase see [[N-acetylneuraminate lyase]]
}}
}}
[[Category: Topic Page]]
[[Category: Topic Page]]

Current revision

3D structures of Aldolase

Updated on 19-September-2024

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

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