User:Leah Goehring/Sandbox 1
From Proteopedia
< User:Leah Goehring(Difference between revisions)
(New page: ==Your Heading Here (maybe something like 'Structure')== <StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''> This is a default text for you...) |
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| - | = | + | =Sterol O-acyltransferase (SOAT)= |
| - | <StructureSection load=' | + | <StructureSection load='6l47' size='350' frame='true' side='right' caption='Sterol O-acyltransferase 6147' scene=''> |
This is a default text for your page '''Leah Goehring/Sandbox 1'''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | This is a default text for your page '''Leah Goehring/Sandbox 1'''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | ||
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | ||
| - | == | + | ==Introduction== |
| + | [[Image:SOAT.png|400 px|right|thumb|Figure 1. Dimer of dimer of SOAT]] | ||
| + | == Function == | ||
| + | ===Active Site=== | ||
== Disease == | == Disease == | ||
== Relevance == | == Relevance == | ||
| - | + | [https://www.alz.org/alzheimers-dementia/what-is-alzheimers Alzheimer's Disease] | |
== Structural highlights == | == Structural highlights == | ||
| - | This is a sample scene created with SAT to <scene name="/ | + | This is a sample scene created with SAT to <scene name="<scene name='87/877508/Histidine_residues/1'>Histidines</scene>">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. <ref name="Ransey">PMID:28504306</ref> <ref name="Guan">PMID:32424158</ref> |
</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
<references/> | <references/> | ||
| + | |||
| + | ==Student Contributors== | ||
| + | *Leah Goehring | ||
| + | *Gabby Smith | ||
| + | *Madison Unger | ||
| + | *Anna Campbell | ||
Current revision
Sterol O-acyltransferase (SOAT)
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References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
- ↑ Ransey E, Paredes E, Dey SK, Das SR, Heroux A, Macbeth MR. Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 reveals a catalytic Zn(2+) /Mn(2+) heterobinucleation. FEBS Lett. 2017 Jul;591(13):2003-2010. doi: 10.1002/1873-3468.12677. Epub 2017, Jun 14. PMID:28504306 doi:http://dx.doi.org/10.1002/1873-3468.12677
- ↑ Guan C, Niu Y, Chen SC, Kang Y, Wu JX, Nishi K, Chang CCY, Chang TY, Luo T, Chen L. Structural insights into the inhibition mechanism of human sterol O-acyltransferase 1 by a competitive inhibitor. Nat Commun. 2020 May 18;11(1):2478. doi: 10.1038/s41467-020-16288-4. PMID:32424158 doi:http://dx.doi.org/10.1038/s41467-020-16288-4
Student Contributors
- Leah Goehring
- Gabby Smith
- Madison Unger
- Anna Campbell
