User:Leah Goehring/Sandbox 1

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=Sterol O-acyltransferase (SOAT)=
=Sterol O-acyltransferase (SOAT)=
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<StructureSection load='6l47' size='350' frame='true' side='right' caption='Sterol O-acyltransferase 6147' scene=''>
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<StructureSection load='6l47' size='350' frame='true' side='right' caption='Sterol O-acyltransferase 6147' scene=''>
This is a default text for your page '''Leah Goehring/Sandbox 1'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
This is a default text for your page '''Leah Goehring/Sandbox 1'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
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== Function ==
== Function ==
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===Active Site===
== Disease ==
== Disease ==
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== Structural highlights ==
== Structural highlights ==
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This is a sample scene created with SAT to <scene name="<scene name='87/877508/Histidine_residues/1'>Histidines</scene>">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
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This is a sample scene created with SAT to <scene name="<scene name='87/877508/Histidine_residues/1'>Histidines</scene>">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. <ref name="Ransey">PMID:28504306</ref> <ref name="Guan">PMID:32424158</ref>
</StructureSection>
</StructureSection>

Current revision

Sterol O-acyltransferase (SOAT)

Sterol O-acyltransferase 6147

Drag the structure with the mouse to rotate

References

  1. Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
  2. Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
  3. Ransey E, Paredes E, Dey SK, Das SR, Heroux A, Macbeth MR. Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 reveals a catalytic Zn(2+) /Mn(2+) heterobinucleation. FEBS Lett. 2017 Jul;591(13):2003-2010. doi: 10.1002/1873-3468.12677. Epub 2017, Jun 14. PMID:28504306 doi:http://dx.doi.org/10.1002/1873-3468.12677
  4. Guan C, Niu Y, Chen SC, Kang Y, Wu JX, Nishi K, Chang CCY, Chang TY, Luo T, Chen L. Structural insights into the inhibition mechanism of human sterol O-acyltransferase 1 by a competitive inhibitor. Nat Commun. 2020 May 18;11(1):2478. doi: 10.1038/s41467-020-16288-4. PMID:32424158 doi:http://dx.doi.org/10.1038/s41467-020-16288-4

Student Contributors

  • Leah Goehring
  • Gabby Smith
  • Madison Unger
  • Anna Campbell

Proteopedia Page Contributors and Editors (what is this?)

Leah Goehring

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