7m1z
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Targeting Enterococcus faecalis HMG-CoA reductase with a novel non-statin inhibitor== | |
| + | <StructureSection load='7m1z' size='340' side='right'caption='[[7m1z]], [[Resolution|resolution]] 2.27Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[7m1z]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterococcus_faecalis Enterococcus faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7M1Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7M1Z FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.27Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HMG:3-HYDROXY-3-METHYLGLUTARYL-COENZYME+A'>HMG</scene>, <scene name='pdbligand=MEV:(R)-MEVALONATE'>MEV</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7m1z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7m1z OCA], [https://pdbe.org/7m1z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7m1z RCSB], [https://www.ebi.ac.uk/pdbsum/7m1z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7m1z ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q835L3_ENTFA Q835L3_ENTFA] | ||
| - | + | ==See Also== | |
| - | + | *[[HMG-CoA Reductase 3D structures|HMG-CoA Reductase 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Enterococcus faecalis]] |
| - | [[Category: Bose | + | [[Category: Large Structures]] |
| - | [[Category: Steussy | + | [[Category: Bose S]] |
| + | [[Category: Stauffacher CV]] | ||
| + | [[Category: Steussy CN]] | ||
Current revision
Targeting Enterococcus faecalis HMG-CoA reductase with a novel non-statin inhibitor
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