7m3x
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of the Apo Form of Human RBBP7== | |
| + | <StructureSection load='7m3x' size='340' side='right'caption='[[7m3x]], [[Resolution|resolution]] 1.46Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[7m3x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7M3X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7M3X FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.46Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7m3x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7m3x OCA], [https://pdbe.org/7m3x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7m3x RCSB], [https://www.ebi.ac.uk/pdbsum/7m3x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7m3x ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RBBP7_HUMAN RBBP7_HUMAN] Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assembly following DNA replication; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; and the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex.<ref>PMID:10866654</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Retinoblastoma-binding protein 3D structures|Retinoblastoma-binding protein 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Arrowsmith CH]] |
| - | [[Category: | + | [[Category: Dong A]] |
| - | [[Category: | + | [[Category: Edwards AM]] |
| - | [[Category: | + | [[Category: Halabelian L]] |
| - | [[Category: | + | [[Category: Hutchinson A]] |
| + | [[Category: Li Y]] | ||
| + | [[Category: Righetto GL]] | ||
| + | [[Category: Seitova A]] | ||
Current revision
Crystal Structure of the Apo Form of Human RBBP7
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Dong A | Edwards AM | Halabelian L | Hutchinson A | Li Y | Righetto GL | Seitova A
