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7dvg
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of rice immune receptor RGA5-HMA5 mutant.== | |
| - | + | <StructureSection load='7dvg' size='340' side='right'caption='[[7dvg]], [[Resolution|resolution]] 2.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7dvg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryza_sativa_Japonica_Group Oryza sativa Japonica Group]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DVG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DVG FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7dvg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7dvg OCA], [https://pdbe.org/7dvg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7dvg RCSB], [https://www.ebi.ac.uk/pdbsum/7dvg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7dvg ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RGA5R_ORYSJ RGA5R_ORYSJ] Disease resistance (R) protein that recognizes the AVR-Pia and AVR1-CO39 effector avirulence proteins from M.oryzae. Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth. Contribution of RGA4 is required to recognize the effector avirulence proteins AVR-Pia and AVR1-CO39 from M.oryzae (PubMed:21251109, PubMed:23548743). Acts as a repressor of the RGA4-mediated cell death activation. Upon infection, recognition and binding of the AVR effectors relieve the RGA5-mediated repression and triggers the hypersensitive response (PubMed:25024433). Immune response triggered by the RGA4-RGA5 -mediated recognition of AVR1-CO39 confers resistance to X.oryzae pathovars (PubMed:27289079).<ref>PMID:21251109</ref> <ref>PMID:23548743</ref> <ref>PMID:25024433</ref> <ref>PMID:27289079</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Oryza sativa Japonica Group]] | ||
| + | [[Category: Liu JF]] | ||
| + | [[Category: Zhang X]] | ||
Current revision
Crystal structure of rice immune receptor RGA5-HMA5 mutant.
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