1ih6
From Proteopedia
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1ih6]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IH6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IH6 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1ih6]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IH6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IH6 FirstGlance]. <br> | ||
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CBR:5-BROMO-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>CBR</scene></td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ih6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ih6 OCA], [https://pdbe.org/1ih6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ih6 RCSB], [https://www.ebi.ac.uk/pdbsum/1ih6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ih6 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ih6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ih6 OCA], [https://pdbe.org/1ih6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ih6 RCSB], [https://www.ebi.ac.uk/pdbsum/1ih6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ih6 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | <div style="background-color:#fffaf0;"> | ||
| - | == Publication Abstract from PubMed == | ||
| - | The transition between B- and A-DNA was first observed nearly 50 years ago. We have now mapped this transformation through a set of single-crystal structures of the sequence d(GGCGCC)2, with various intermediates being trapped by methylating or brominating the cytosine bases. The resulting pathway progresses through 13 conformational steps, with a composite structure that pairs A-nucleotides with complementary B-nucleotides serving as a distinct transition intermediate. The details of each step in the conversion of B- to A-DNA are thus revealed at the atomic level, placing intermediates for this and other sequences in the context of a common pathway. | ||
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| - | A crystallographic map of the transition from B-DNA to A-DNA.,Vargason JM, Henderson K, Ho PS Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7265-70. Epub 2001 Jun 5. PMID:11390969<ref>PMID:11390969</ref> | ||
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| - | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| - | </div> | ||
| - | <div class="pdbe-citations 1ih6" style="background-color:#fffaf0;"></div> | ||
| - | == References == | ||
| - | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Henderson | + | [[Category: Henderson K]] |
| - | [[Category: Ho | + | [[Category: Ho PS]] |
| - | [[Category: Vargason | + | [[Category: Vargason JM]] |
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Current revision
Multi-Conformation Crystal Structure of GGBr5CGCC
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