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2kjy
From Proteopedia
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==MYPT1(658-714)== | ==MYPT1(658-714)== | ||
| - | <StructureSection load='2kjy' size='340' side='right'caption='[[2kjy | + | <StructureSection load='2kjy' size='340' side='right'caption='[[2kjy]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2kjy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2kjy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KJY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KJY FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kjy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kjy OCA], [https://pdbe.org/2kjy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kjy RCSB], [https://www.ebi.ac.uk/pdbsum/2kjy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kjy ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kjy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kjy OCA], [https://pdbe.org/2kjy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kjy RCSB], [https://www.ebi.ac.uk/pdbsum/2kjy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kjy ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/MYPT1_HUMAN MYPT1_HUMAN] Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN-dependent suppression of HIF1A activity.<ref>PMID:19245366</ref> <ref>PMID:18477460</ref> <ref>PMID:20354225</ref> | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Eto | + | [[Category: Eto M]] |
| - | [[Category: Iwaoka | + | [[Category: Iwaoka R]] |
| - | [[Category: Mori | + | [[Category: Mori S]] |
| - | [[Category: Ohki | + | [[Category: Ohki S]] |
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Current revision
MYPT1(658-714)
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Categories: Homo sapiens | Large Structures | Eto M | Iwaoka R | Mori S | Ohki S
