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2klh

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Current revision (19:12, 29 May 2024) (edit) (undo)
 
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==NMR Structure of RCL in complex with GMP==
==NMR Structure of RCL in complex with GMP==
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<StructureSection load='2klh' size='340' side='right'caption='[[2klh]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
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<StructureSection load='2klh' size='340' side='right'caption='[[2klh]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2klh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KLH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KLH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2klh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KLH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KLH FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Rcl ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2klh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2klh OCA], [https://pdbe.org/2klh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2klh RCSB], [https://www.ebi.ac.uk/pdbsum/2klh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2klh ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2klh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2klh OCA], [https://pdbe.org/2klh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2klh RCSB], [https://www.ebi.ac.uk/pdbsum/2klh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2klh ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/DNPH1_RAT DNPH1_RAT]] Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases.<ref>PMID:17234634</ref>
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[https://www.uniprot.org/uniprot/DNPH1_RAT DNPH1_RAT] Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases.<ref>PMID:17234634</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Buffalo rat]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Kaminski, P A]]
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[[Category: Rattus norvegicus]]
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[[Category: Labesse, G]]
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[[Category: Kaminski PA]]
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[[Category: Padilla, A]]
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[[Category: Labesse G]]
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[[Category: Yang, Y]]
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[[Category: Padilla A]]
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[[Category: Zhang, C]]
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[[Category: Yang Y]]
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[[Category: Gmp]]
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[[Category: Zhang C]]
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[[Category: Hydrolase]]
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[[Category: N-glycosidase]]
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[[Category: Nucleus]]
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[[Category: Phosphoprotein]]
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[[Category: Protein]]
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Current revision

NMR Structure of RCL in complex with GMP

PDB ID 2klh

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