2krm
From Proteopedia
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==RDC refined solution structure of the first SH3 domain of CD2AP== | ==RDC refined solution structure of the first SH3 domain of CD2AP== | ||
| - | <StructureSection load='2krm' size='340' side='right'caption='[[2krm | + | <StructureSection load='2krm' size='340' side='right'caption='[[2krm]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2krm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2krm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KRM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KRM FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2krm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2krm OCA], [https://pdbe.org/2krm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2krm RCSB], [https://www.ebi.ac.uk/pdbsum/2krm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2krm ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2krm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2krm OCA], [https://pdbe.org/2krm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2krm RCSB], [https://www.ebi.ac.uk/pdbsum/2krm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2krm ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/CD2AP_MOUSE CD2AP_MOUSE] Required for cytokinesis (By similarity). Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus.<ref>PMID:10514378</ref> | |
==See Also== | ==See Also== | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Mus musculus]] |
| - | [[Category: Azuaga | + | [[Category: Azuaga AI]] |
| - | + | [[Category: Ortega Roldan JAJ]] | |
| - | [[Category: Roldan | + | [[Category: Van Nuland NAJ]] |
| - | [[Category: | + | |
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Current revision
RDC refined solution structure of the first SH3 domain of CD2AP
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