7m4j

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'''Unreleased structure'''
 
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The entry 7m4j is ON HOLD until Paper Publication
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==DNA Polymerase Lambda, dCTP:At Mn2+ Product State Ternary Complex, 960 min==
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<StructureSection load='7m4j' size='340' side='right'caption='[[7m4j]], [[Resolution|resolution]] 2.38&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7m4j]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7M4J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7M4J FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.377&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7m4j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7m4j OCA], [https://pdbe.org/7m4j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7m4j RCSB], [https://www.ebi.ac.uk/pdbsum/7m4j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7m4j ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DPOLL_HUMAN DPOLL_HUMAN] Repair polymerase. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.<ref>PMID:11457865</ref> <ref>PMID:15537631</ref>
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Authors:
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==See Also==
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*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
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Description:
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== References ==
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[[Category: Unreleased Structures]]
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Jamsen JA]]
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[[Category: Wilson SH]]

Current revision

DNA Polymerase Lambda, dCTP:At Mn2+ Product State Ternary Complex, 960 min

PDB ID 7m4j

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