7bhx

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==Crystal structure of MAT2a bound to allosteric inhibitor (compound 31)==
==Crystal structure of MAT2a bound to allosteric inhibitor (compound 31)==
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<StructureSection load='7bhx' size='340' side='right'caption='[[7bhx]]' scene=''>
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<StructureSection load='7bhx' size='340' side='right'caption='[[7bhx]], [[Resolution|resolution]] 1.08&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BHX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BHX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7bhx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BHX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BHX FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bhx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bhx OCA], [https://pdbe.org/7bhx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bhx RCSB], [https://www.ebi.ac.uk/pdbsum/7bhx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bhx ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.08&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=TO5:7-chloranyl-4-(dimethylamino)-1-pyridin-3-yl-quinazolin-2-one'>TO5</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bhx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bhx OCA], [https://pdbe.org/7bhx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bhx RCSB], [https://www.ebi.ac.uk/pdbsum/7bhx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bhx ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/METK2_HUMAN METK2_HUMAN] Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
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==See Also==
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*[[S-adenosylmethionine synthetase 3D structures|S-adenosylmethionine synthetase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Argyrou A]]
[[Category: Argyrou A]]

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Crystal structure of MAT2a bound to allosteric inhibitor (compound 31)

PDB ID 7bhx

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