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7oa5
From Proteopedia
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| - | ==== | + | ==RUVA COMPLEXED TO A HOLLIDAY JUNCTION.== |
| - | <StructureSection load='7oa5' size='340' side='right'caption='[[7oa5]]' scene=''> | + | <StructureSection load='7oa5' size='340' side='right'caption='[[7oa5]], [[Resolution|resolution]] 2.38Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7oa5]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_leprae Mycobacterium leprae] and [https://en.wikipedia.org/wiki/Mycobacterium_leprae_TN Mycobacterium leprae TN]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1bvs 1bvs]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7OA5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7OA5 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7oa5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7oa5 OCA], [https://pdbe.org/7oa5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7oa5 RCSB], [https://www.ebi.ac.uk/pdbsum/7oa5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7oa5 ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.378Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7oa5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7oa5 OCA], [https://pdbe.org/7oa5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7oa5 RCSB], [https://www.ebi.ac.uk/pdbsum/7oa5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7oa5 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RUVA_MYCLE RUVA_MYCLE] The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity). | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Helicase 3D structures|Helicase 3D structures]] | ||
| + | *[[Resolvase 3D structures|Resolvase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Mycobacterium leprae]] |
| + | [[Category: Mycobacterium leprae TN]] | ||
| + | [[Category: Pearl LH]] | ||
| + | [[Category: Roe SM]] | ||
Current revision
RUVA COMPLEXED TO A HOLLIDAY JUNCTION.
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