6v04

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<StructureSection load='6v04' size='340' side='right'caption='[[6v04]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='6v04' size='340' side='right'caption='[[6v04]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6v04]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_53710 Atcc 53710]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6V04 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6V04 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6v04]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Micromonospora_chersina Micromonospora chersina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6V04 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6V04 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GA0070603_4194 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=47854 ATCC 53710])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6v04 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6v04 OCA], [https://pdbe.org/6v04 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6v04 RCSB], [https://www.ebi.ac.uk/pdbsum/6v04 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6v04 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6v04 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6v04 OCA], [https://pdbe.org/6v04 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6v04 RCSB], [https://www.ebi.ac.uk/pdbsum/6v04 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6v04 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/B2BM46_9ACTN B2BM46_9ACTN]
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The 1.5 A resolution crystal structure of DynU16, a protein identified in the dynemicin-biosynthetic gene cluster, is reported. The structure adopts a di-domain helix-grip fold with a uniquely positioned open cavity connecting the domains. The elongated dimensions of the cavity appear to be compatible with the geometry of a linear polyene, suggesting the involvement of DynU16 in the upstream steps of dynemicin biosynthesis.
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Structural characterization of DynU16, a START/Bet v1-like protein involved in dynemicin biosynthesis.,Alvarado SK, Miller MD, Bhardwaj M, Thorson JS, Van Lanen SG, Phillips GN Jr Acta Crystallogr F Struct Biol Commun. 2021 Oct 1;77(Pt 10):328-333. doi:, 10.1107/S2053230X21008943. Epub 2021 Sep 21. PMID:34605436<ref>PMID:34605436</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 6v04" style="background-color:#fffaf0;"></div>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 53710]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Alvarado, S K]]
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[[Category: Micromonospora chersina]]
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[[Category: Bhardwaj, M]]
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[[Category: Alvarado SK]]
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[[Category: Lanen, S G.Van]]
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[[Category: Bhardwaj M]]
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[[Category: Miller, M D]]
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[[Category: Miller MD]]
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[[Category: Philips, G N]]
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[[Category: Phillips Jr GN]]
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[[Category: Thorson, J S]]
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[[Category: Thorson JS]]
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[[Category: Cyclase/aromatase]]
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[[Category: Van Lanen SG]]
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[[Category: Dynemicin]]
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[[Category: Srpbcc domain]]
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[[Category: Start domain]]
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[[Category: Unknown function]]
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Current revision

DynU16 crystal structure, a putative protein in the dynemicin biosynthetic locus

PDB ID 6v04

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