1kyw

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<StructureSection load='1kyw' size='340' side='right'caption='[[1kyw]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='1kyw' size='340' side='right'caption='[[1kyw]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1kyw]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Alfalfa Alfalfa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KYW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KYW FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1kyw]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Medicago_sativa Medicago sativa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KYW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KYW FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HFL:5-(3,3-DIHYDROXYPROPENY)-3-METHOXY-BENZENE-1,2-DIOL'>HFL</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1kyz|1kyz]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HFL:5-(3,3-DIHYDROXYPROPENY)-3-METHOXY-BENZENE-1,2-DIOL'>HFL</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Caffeate_O-methyltransferase Caffeate O-methyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.68 2.1.1.68] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kyw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kyw OCA], [https://pdbe.org/1kyw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kyw RCSB], [https://www.ebi.ac.uk/pdbsum/1kyw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kyw ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kyw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kyw OCA], [https://pdbe.org/1kyw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kyw RCSB], [https://www.ebi.ac.uk/pdbsum/1kyw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kyw ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/COMT1_MEDSA COMT1_MEDSA]] Catalyzes the conversion of caffeic acid to ferulic acid and of 5-hydroxyferulic acid to sinapic acid. The resulting products may subsequently be converted to the corresponding alcohols that are incorporated into lignins.
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[https://www.uniprot.org/uniprot/COMT1_MEDSA COMT1_MEDSA] Catalyzes the conversion of caffeic acid to ferulic acid and of 5-hydroxyferulic acid to sinapic acid. The resulting products may subsequently be converted to the corresponding alcohols that are incorporated into lignins.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ky/1kyw_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ky/1kyw_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Alfalfa]]
 
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[[Category: Caffeate O-methyltransferase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Dixon, R A]]
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[[Category: Medicago sativa]]
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[[Category: Ferrer, J L]]
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[[Category: Dixon RA]]
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[[Category: Kota, P]]
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[[Category: Ferrer J-L]]
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[[Category: Noel, J P]]
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[[Category: Kota P]]
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[[Category: Zubieta, C]]
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[[Category: Noel JP]]
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[[Category: Lignification]]
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[[Category: Zubieta C]]
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[[Category: O-methyltransferase]]
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[[Category: Protein-ligand complex]]
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[[Category: Transferase]]
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Current revision

Crystal Structure Analysis of Caffeic Acid/5-hydroxyferulic acid 3/5-O-methyltransferase in complex with 5-hydroxyconiferaldehyde

PDB ID 1kyw

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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