7oat

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:52, 7 February 2024) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 7oat is ON HOLD
+
==Structural basis for targeted p97 remodelling by ASPL as prerequisite for p97 trimethylation by METTL21D==
-
 
+
<StructureSection load='7oat' size='340' side='right'caption='[[7oat]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
-
Authors: Petrovic, S., Heinemann, U., Roske, Y.
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[7oat]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7OAT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7OAT FirstGlance]. <br>
-
Description: Structural basis for targeted p97 remodelling by ASPL as prerequisite for p97 trimethylation by METTL21D
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.995&#8491;</td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
-
[[Category: Heinemann, U]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7oat FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7oat OCA], [https://pdbe.org/7oat PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7oat RCSB], [https://www.ebi.ac.uk/pdbsum/7oat PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7oat ProSAT]</span></td></tr>
-
[[Category: Petrovic, S]]
+
</table>
-
[[Category: Roske, Y]]
+
== Disease ==
 +
[https://www.uniprot.org/uniprot/ASPC1_HUMAN ASPC1_HUMAN] Translocation renal cell carcinoma;Alveolar soft-tissue sarcoma. A chromosomal aberration involving ASPSCR1 is found in patients with alveolar soft part sarcoma. Translocation t(X;17)(p11;q25) with TFE3 forms a ASPSCR1-TFE3 fusion protein.<ref>PMID:11244503</ref> A chromosomal aberration involving ASPSCR1 has been found in two patients with of papillary renal cell carcinoma. Translocation t(X;17)(p11.2;q25).<ref>PMID:11358836</ref>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/ASPC1_HUMAN ASPC1_HUMAN] Tethering protein that sequesters GLUT4-containing vesicles in the cytoplasm in the absence of insulin. Modulates the amount of GLUT4 that is available at the cell surface (By similarity). Enhances VCP methylation catalyzed by VCPKMT.<ref>PMID:23349634</ref>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Homo sapiens]]
 +
[[Category: Large Structures]]
 +
[[Category: Heinemann U]]
 +
[[Category: Petrovic S]]
 +
[[Category: Roske Y]]

Current revision

Structural basis for targeted p97 remodelling by ASPL as prerequisite for p97 trimethylation by METTL21D

PDB ID 7oat

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/7oat"
Personal tools