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7ofq
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | The | + | ==The archaellum of Methanocaldococcus villosus== |
| + | <StructureSection load='7ofq' size='340' side='right'caption='[[7ofq]], [[Resolution|resolution]] 3.08Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[7ofq]] is a 45 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_villosus Methanocaldococcus villosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7OFQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7OFQ FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.08Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ofq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ofq OCA], [https://pdbe.org/7ofq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ofq RCSB], [https://www.ebi.ac.uk/pdbsum/7ofq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ofq ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Archaea use a molecular machine, called the archaellum, to swim. The archaellum consists of an ATP-powered intracellular motor that drives the rotation of an extracellular filament composed of multiple copies of proteins named archaellins. In many species, several archaellin homologs are encoded in the same operon; however, previous structural studies indicated that archaellum filaments mainly consist of only one protein species. Here, we use electron cryo-microscopy to elucidate the structure of the archaellum from Methanocaldococcus villosus at 3.08 A resolution. The filament is composed of two alternating archaellins, suggesting that the architecture and assembly of archaella is more complex than previously thought. Moreover, we identify structural elements that may contribute to the filament's flexibility. | ||
| - | + | An archaellum filament composed of two alternating subunits.,Gambelli L, Isupov MN, Conners R, McLaren M, Bellack A, Gold V, Rachel R, Daum B Nat Commun. 2022 Feb 7;13(1):710. doi: 10.1038/s41467-022-28337-1. PMID:35132062<ref>PMID:35132062</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| - | [[Category: | + | <div class="pdbe-citations 7ofq" style="background-color:#fffaf0;"></div> |
| - | [[Category: Daum | + | == References == |
| - | [[Category: Gambelli | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Methanocaldococcus villosus]] | ||
| + | [[Category: Daum B]] | ||
| + | [[Category: Gambelli L]] | ||
| + | [[Category: Isupov M]] | ||
Current revision
The archaellum of Methanocaldococcus villosus
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