2lca

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==Solution structure of the C domain of RV0899 from mycobacterium tuberculosis==
==Solution structure of the C domain of RV0899 from mycobacterium tuberculosis==
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<StructureSection load='2lca' size='340' side='right'caption='[[2lca]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2lca' size='340' side='right'caption='[[2lca]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2lca]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LCA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LCA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2lca]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LCA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LCA FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Rv0899, MT0922, MTCY31.27 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lca FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lca OCA], [https://pdbe.org/2lca PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lca RCSB], [https://www.ebi.ac.uk/pdbsum/2lca PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lca ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lca FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lca OCA], [https://pdbe.org/2lca PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lca RCSB], [https://www.ebi.ac.uk/pdbsum/2lca PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lca ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ARFA_MYCTU ARFA_MYCTU] Probably plays a role in ammonia secretion that neutralizes the medium at pH 5.5, although it does not play a direct role in ammonia transport. The OmpA-like domain (196-326) binds M.tuberculosis peptidoglycan. Overexpression in M.bovis or M.smegmatis gives channels with average conductance value of 1,600 +/- 100 pS, but this may not be physiologically relevant.<ref>PMID:12366842</ref> <ref>PMID:17573469</ref> <ref>PMID:21410778</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Marassi, F]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Yao, Y]]
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[[Category: Marassi F]]
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[[Category: Peptidoglycan-binding protein]]
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[[Category: Yao Y]]

Current revision

Solution structure of the C domain of RV0899 from mycobacterium tuberculosis

PDB ID 2lca

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