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2lp4

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==Solution structure of P1-CheY/P2 complex in bacterial chemotaxis==
==Solution structure of P1-CheY/P2 complex in bacterial chemotaxis==
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<StructureSection load='2lp4' size='340' side='right'caption='[[2lp4]], [[NMR_Ensembles_of_Models | 25 NMR models]]' scene=''>
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<StructureSection load='2lp4' size='340' side='right'caption='[[2lp4]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2lp4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LP4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LP4 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2lp4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LP4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LP4 FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1i5n|1i5n]], [[1eay|1eay]]</div></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cheA, b1888, JW1877 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI]), cheY, b1882, JW1871 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lp4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lp4 OCA], [https://pdbe.org/2lp4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lp4 RCSB], [https://www.ebi.ac.uk/pdbsum/2lp4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lp4 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lp4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lp4 OCA], [https://pdbe.org/2lp4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lp4 RCSB], [https://www.ebi.ac.uk/pdbsum/2lp4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lp4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/CHEA_ECOLI CHEA_ECOLI]] Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY. [[https://www.uniprot.org/uniprot/CHEY_ECOLI CHEY_ECOLI]] Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. In its active (phosphorylated or acetylated) form, CheY exhibits enhanced binding to a switch component, FliM, at the flagellar motor which induces a change from counterclockwise to clockwise flagellar rotation. Overexpression of CheY in association with MotA and MotB improves motility of a ycgR disruption, suggesting there is an interaction (direct or indirect) between the c-di-GMP-binding flagellar brake protein and the flagellar stator.<ref>PMID:20346719</ref>
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[https://www.uniprot.org/uniprot/CHEA_ECOLI CHEA_ECOLI] Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ecoli]]
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[[Category: Escherichia coli K-12]]
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[[Category: Histidine kinase]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Dahlquist, F]]
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[[Category: Dahlquist F]]
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[[Category: Kamamura, T]]
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[[Category: Kamamura T]]
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[[Category: Mo, G]]
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[[Category: Mo G]]
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[[Category: Zhou, H]]
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[[Category: Zhou H]]
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[[Category: Histidine phosphotransfer domain]]
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[[Category: Response regulator]]
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[[Category: Transferase-signaling protein complex]]
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[[Category: Two component signaling system]]
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Current revision

Solution structure of P1-CheY/P2 complex in bacterial chemotaxis

PDB ID 2lp4

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