2lx7
From Proteopedia
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==Solution NMR structure of SH3 domain of growth arrest-specific protein 7 (GAS7) (fragment 1-60) from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR8574A== | ==Solution NMR structure of SH3 domain of growth arrest-specific protein 7 (GAS7) (fragment 1-60) from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR8574A== | ||
- | <StructureSection load='2lx7' size='340' side='right'caption='[[2lx7 | + | <StructureSection load='2lx7' size='340' side='right'caption='[[2lx7]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[2lx7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2lx7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LX7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LX7 FirstGlance]. <br> |
- | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lx7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lx7 OCA], [https://pdbe.org/2lx7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lx7 RCSB], [https://www.ebi.ac.uk/pdbsum/2lx7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lx7 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lx7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lx7 OCA], [https://pdbe.org/2lx7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lx7 RCSB], [https://www.ebi.ac.uk/pdbsum/2lx7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lx7 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
- | + | [https://www.uniprot.org/uniprot/GAS7_HUMAN GAS7_HUMAN] Note=A chromosomal aberration involving GAS7 is found in acute myeloid leukemia. Translocation t(11;17)(q23;p13) with MLL/HRX. | |
== Function == | == Function == | ||
- | + | [https://www.uniprot.org/uniprot/GAS7_HUMAN GAS7_HUMAN] May play a role in promoting maturation and morphological differentiation of cerebellar neurons. | |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
- | [[Category: Acton | + | [[Category: Acton T]] |
- | [[Category: Dan | + | [[Category: Dan L]] |
- | [[Category: Everett | + | [[Category: Everett JK]] |
- | [[Category: Janjua | + | [[Category: Janjua H]] |
- | [[Category: Kennedy | + | [[Category: Kennedy MA]] |
- | [[Category: Kohan | + | [[Category: Kohan E]] |
- | [[Category: Montelione | + | [[Category: Montelione GT]] |
- | + | [[Category: Ramelot TA]] | |
- | [[Category: Ramelot | + | [[Category: Xiao R]] |
- | [[Category: Xiao | + | [[Category: Yang Y]] |
- | [[Category: Yang | + | |
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Current revision
Solution NMR structure of SH3 domain of growth arrest-specific protein 7 (GAS7) (fragment 1-60) from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR8574A
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Categories: Homo sapiens | Large Structures | Acton T | Dan L | Everett JK | Janjua H | Kennedy MA | Kohan E | Montelione GT | Ramelot TA | Xiao R | Yang Y